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Archive for the ‘life extension’ category: Page 650

Aug 15, 2012

Approaching the Great Rescue

Posted by in categories: biological, biotech/medical, business, chemistry, complex systems, education, engineering, ethics, events, evolution, existential risks, futurism, geopolitics, homo sapiens, human trajectories, life extension, media & arts, neuroscience, philosophy, policy, singularity, sustainability, transparency

http://www.sciencedaily.com/releases/2012/08/120815131137.htm

One more step has been taken toward making whole body cryopreservation a practical reality. An understanding of the properties of water allows the temperature of the human body to be lowered without damaging cell structures.

Just as the microchip revolution was unforeseen the societal effects of suspending death have been overlooked completely.

The first successful procedure to freeze a human being and then revive that person without damage at a later date will be the most important single event in human history. When that person is revived he or she will awaken to a completely different world.

Continue reading “Approaching the Great Rescue” »

Jan 13, 2012

Verne, Wells, and the Obvious Future Part 2

Posted by in categories: asteroid/comet impacts, biotech/medical, business, defense, economics, education, engineering, ethics, events, evolution, existential risks, futurism, life extension, lifeboat, media & arts, military, nuclear weapons, philosophy, physics, policy, space

I am taking the advice of a reader of this blog and devoting part 2 to examples of old school and modern movies and the visionary science they portray.

Things to Come 1936 — Event Horizon 1997
Things to Come was a disappointment to Wells and Event Horizon was no less a disappointment to audiences. I found them both very interesting as a showcase for some technology and social challenges.… to come- but a little off the mark in regards to the exact technology and explicit social issues. In the final scene of Things to Come, Raymond Massey asks if mankind will choose the stars. What will we choose? I find this moment very powerful- perhaps the example; the most eloguent expression of the whole genre of science fiction. Event Horizon was a complete counterpoint; a horror movie set in space with a starship modeled after a gothic cathedral. Event Horizon had a rescue crew put in stasis for a high G several month journey to Neptune on a fusion powered spaceship. High accelleration and fusion brings H-bombs to mind, and though not portrayed, this propulsion system is in fact a most probable future. Fusion “engines” are old hat in sci-fi despite the near certainty the only places fusion will ever work as advertised are in a bomb or a star. The Event Horizon, haunted and consigned to hell, used a “gravity drive” to achieve star travel by “folding space.” Interestingly, a recent concept for a black hole powered starship is probably the most accurate forecast of the technology that will be used for interstellar travel in the next century. While ripping a hole in the fabric of space time may be strictly science fantasy, for the next thousand years at least, small singularity propulsion using Hawking radiation to achieve a high fraction of the speed of light is mathematically sound and the most obvious future.

https://lifeboat.com/blog/2012/09/only-one-star-drive-can-work-so-far

That is, if humanity avoids an outbreak of engineered pathogens or any one of several other threats to our existence in that time frame.

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Jan 4, 2012

Journal for Biological & Health Innovation

Posted by in categories: biological, biotech/medical, business, education, futurism, life extension, philosophy

The Journal for Biological & Health Innovation is accepting papers for peer review now. This journal is specific to Africa and our thoughts, theory, research, practice could have a huge impact on the expeditious development of the rest of the world technologically.

Nov 13, 2011

D’Nile aint just a river in Egypt…

Posted by in categories: business, complex systems, cosmology, economics, education, ethics, existential risks, finance, futurism, geopolitics, human trajectories, humor, life extension, lifeboat, media & arts, neuroscience, open access, open source, philosophy, policy, rants, robotics/AI, space, sustainability

Greetings fellow travelers, please allow me to introduce myself; I’m Mike ‘Cyber Shaman’ Kawitzky, independent film maker and writer from Cape Town, South Africa, one of your media/art contributors/co-conspirators.

It’s a bit daunting posting to such an illustrious board, so let me try to imagine, with you; how to regard the present with nostalgia while looking look forward to the past, knowing that a millisecond away in the future exists thoughts to think; it’s the mode of neural text, reverse causality, non-locality and quantum entanglement, where the traveller is the journey into a world in transition; after 9/11, after the economic meltdown, after the oil spill, after the tsunami, after Fukushima, after 21st Century melancholia upholstered by anti-psychotic drugs help us forget ‘the good old days’; because it’s business as usual for the 1%; the rest continue downhill with no brakes. Can’t wait to see how it all works out.

Please excuse me, my time machine is waiting…
Post cyberpunk and into Transhumanism

Aug 31, 2011

Life Extension Potential

Posted by in categories: life extension, sustainability

The objective for the body and more specifically cells is to monitor its energy potential and well being just like we’d monitor anything else with a modern information system/information technology (IS/IT).

Apoptosis is an intentional death of a cell that triggers a “natural” death, Necrosis is an unintentional death of a cell due to damage. While there are some inherent dangers with existing and making it as difficult today to avoid necrosis as it was yesterday, we can aim to scientifically identify apoptosis and manage it. Most of us are familiar with apoptosis, we call it cancer…a phenomenon where cells don’t know when to call it quits and we suffer as a result of the growth.

The specific technology doesn’t exist yet, but we require a mechanism to measure and regulate mitochondrion decisions on-demand. Let’s get to work people! Is there a way that we could constantly monitor mitochondrial regulation without losing blood regularly like a the annoying finger prick monitoring that diabetics have to currently endure.

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Aug 28, 2011

George Perry on the Role of Oxidative Stress in Alzheimer’s Disease Interview, June 2011

Posted by in categories: biotech/medical, life extension

http://sciencewatch.com/ana/st/alz2/11monSTAlz2Perr/

Aug 27, 2011

TEDxAlamo — George Perry — Living with Aging: Alzheimer’s, the Disease of Our Time

Posted by in categories: biotech/medical, life extension

Aug 27, 2011

Sciencewatch.com Pays Tribute to Mark A. Smith Special Topic of Alzheimer’s Disease, June 2011

Posted by in categories: biotech/medical, life extension

http://sciencewatch.com/ana/st/alz2/11junSTAlz2Smit/

Aug 27, 2011

Calorie Restriction: A Cell Signaling Diet!

Posted by in categories: biological, life extension

Some people say that a calorie restriction (CR) diet is difficult to follow. It used to be. But things have changed: Thanks to great work by leading scientists, current approaches to calorie restriction are just as much about cell signaling as about limiting calories.

It is known, for example, that serious long-term CR dramatically lowers insulin levels.1 Another hormone, with a similar molecular structure, insulin-like growth factor one (IGF-I), shares the same pathway with insulin and is downregulated by CR in animal studies and by calorie restricted humans who do not follow high protein diets.2

And there’s the rub. For if you hope to benefit from calorie restriction and do not pay attention to the special properties of macronutrient intake, individual foods, and food preparation, you may get an unpleasant surprise: excessive stimulation of the insulin/IGF-I pathway. For example, in a study using healthy volunteers, just 50 grams of white potato starch sends glucose and insulin soaring3 to levels associated with increased risk of cancer, heart disease and diabetes.4

Back in the 1930s, when the term calorie restriction was first applied to Dr. Clive McCay’s rat and mouse experiments,5 it was entirely appropriate because the focus was on calories since he was looking at growth retardation. Of course, little was known about the signals involved in the life-extending effects of the diet. All that changed as scientists discovered important cell-signaling patterns that produce the phenomenal life-transforming effects.6

In 2008, The CR Way took the latest CR science and crafted it into a holistic lifestyle that makes following a CR diet easier by transforming it into a happy, positive lifestyle that focuses on living better now and quite possibly living longer. Recipes, food choices, and lifestyle are deliciously and strategically planned to reduce the insulin / IGF-I pathway activity – making disease risk plummet, while increasing the probability of a longer life.
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1. Fontana L, Meyer T.E., Klein S, Holloszy J.O. Long-Term Calorie Restriction Is Highly Effective In Reducing The Risk For Atherosclerosis In Humans. Proceedings of the National Academy of Science USA 2004;101(17):6659–6663.
2. Fontana L, Klein S, Holloszy J.O. Long-term low-protein low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk. American Journal of Clinical Nutrition. 2006;84:1456–62.
3.Brand-Miller JC, et al. Mean changes in plasma glucose and insulin responses in 10 young adults after consumption of 50g carbohydrates from potato (high-glycemic index; GI) or barley (low-GI) meal. American Journal of Clinical Nutrition. 2005 Aug;82(2):350–4
4. Guideline for Management of Post-meal Glucose, International Diabetes Federation, 2007 ISBN 2−930229−48−9
5. McCay CM, Crowell MF, Maynard LA. Journal of Nutrition. l0:63–79, 1935
6. McGlothin PS, Averill MS. Advances in Calorie restriction. Antiaging Medicine. 2009 Aug;4(4):440–441

Apr 13, 2011

“You are What you Don’t Eat!”

Posted by in categories: biological, life extension

As leaders of calorie restriction research and practice, Meredith Averill and I often participate in media events. A recent news conference covered rapidly evolving aspects of calorie restriction research that anyone could benefit from, whether they choose to follow a low-calorie lifestyle or not. Therefore, we thought it appropriate to share the details of the event with the Lifeboat Foundation audience.

The conference was hosted by the American Federation of Aging Research (AFAR). AFAR is a forward-looking organization that provides financial support for early- and mid-career scientists who are developing careers in the study of aging.

This conference, entitled “You are What you Don’t Eat!” presented two world-famous CR scientists, Drs. Luigi Fontana and Donald Ingram. After an introduction from AFAR’s board member, Dr. Jack Watters, both scientists shared many profound insights that could extend healthy lifespan for millions of people.

Dr. Fontana first reminded us how important calorie restriction research is for the health and financial viability of the health care system: “Cardiovascular disease (CVD), cancer, stroke and diabetes account for nearly 70% of the deaths in the United States and Europe. About 80% of adults over 65 years of age have at least one chronic disease, and 50% have two or more of these chronic diseases that accelerate the aging process1 .” The point he makes is that health care systems, especially with our rapidly aging population cannot sustain this large number of people with disease.

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