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Archive for the ‘neuroscience’ category: Page 154

Jan 29, 2024

SARS-CoV-2 can Infect Dopamine Neurons causing Senescence

Posted by in categories: biotech/medical, chemistry, health, neuroscience

A new study reported that SARS-CoV-2, the virus that causes COVID, can infect dopamine neurons in the brain and trigger senescence—when a cell loses the ability to grow and divide. The researchers from Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center, and Columbia University Vagelos College of Physicians and Surgeons suggest that further research on this finding may shed light on the neurological symptoms associated with long COVID, such as brain fog, lethargy, and depression.

The findings, published in Cell Stem Cell on Jan. 17, show that dopamine neurons infected with SARS-CoV-2 stop working and send out chemical signals that cause inflammation. Normally, these neurons produce dopamine, a neurotransmitter that plays a role in feelings of pleasure, motivation, memory, sleep, and movement. Damage to these neurons is also connected to Parkinson’s disease.

“This project started out to investigate how various types of cells in different organs respond to SARS-CoV-2 infection. We tested lung cells, heart cells, pancreatic beta cells, but the senescence pathway is only activated in dopamine neurons,” said senior author Dr. Shuibing Chen, director of the Center for Genomic Health, the Kilts Family Professor Surgery and a member of the Hartman Institute for Therapeutic Organ Regeneration at Weill Cornell Medicine. “This was a completely unexpected result.”

Jan 29, 2024

70 years of MKUltra, the CIA ‘mind-control’ program that inspired ‘Stranger Things’

Posted by in categories: biotech/medical, chemistry, government, life extension, neuroscience

MKUltra is not referenced explicitly on Stranger Things — the popular Netflix show — but the series seems to be inspired by the controversial CIA program. In the show, a government laboratory is conducting illegal experiments on a young girl and other persons, torturing them, and harnessing their special abilities for their own purposes. This is similar to the goals of the CIA human experimentation project, which was started 70 years ago.

Controversial and unethical experiments were conducted on human subjects by the Agency for the MKUltra project, including the use of mind control techniques and the administration of drugs such as LSD and other chemicals. Electroshock, hypnosis, sensory deprivation, verbal and sexual abuse, and other forms of torture were also part of the non-consensual experiments, which were created because the CIA was convinced that communists had discovered a way to control human minds. Its activities — which were hidden and classified before their files being destroyed after an investigation — remain a subject of concern and investigation to this day.

MKUltra was a CIA program involving the research and development of chemical and biological agents. According to official documents, it was “concerned with the research and development of chemical, biological and radiological materials capable of employment in clandestine operations to control human behavior.”

Jan 28, 2024

Michael Levin Λ Joscha Bach: Collective Intelligence

Posted by in category: neuroscience

Michael Levin and Joscha Bach discuss cognitive science and mind in the context morphogenesis. Sponsors: — Drink Trade: https://www.drinktrade.com/everything

Jan 28, 2024

Neuroscience Says 1 Simple Habit Boosts Brain Connectivity, Learning, and Memory

Posted by in category: neuroscience

Recent neuroscience research helps explain why, when it comes to learning and remembering, writing by hand is better than typing with a keyboard.

Jan 28, 2024

The Sixth Finger

Posted by in categories: evolution, neuroscience

“Where are we going? Life, the timeless, mysterious gift, is still evolving. What wonders, or terrors, does evolution hold in store for us in the next ten thousand years? In a million? In six million? Perhaps the answer lies in this old house in this old and misty valley…” A benign and brilliant scientist (Edward Mulhare) discovers a way to accelerate human evolution. David McCallum (super-agent Illya Kuryakin from “The Man From Uncle”) plays the bitter young coal miner who is miraculously transformed into the man of the future. As a result of the experiment, the size of his brain grows grotesquely, a “sixth finger” appears, and he becomes the possessor of tremendous mental powers!

Jan 27, 2024

Can quantum hints in the brain revive a radical consciousness theory?

Posted by in categories: neuroscience, quantum physics

With anaesthetics and brain organoids, we are finally testing the idea that quantum effects explain consciousness – and the early results suggest this long-derided idea may have been misconstrued.

By George Musser

Jan 27, 2024

No brain, no problem. Jellyfish learn just fine

Posted by in category: neuroscience

Despite lacking a centralized brain, the translucent creatures can learn from past experiences to avoid bumping into obstacles.

Jan 27, 2024

Handwriting May Improve Brain Connectivity More Than Keyboard Typing

Posted by in categories: education, neuroscience

EEG data has shown how brain connectivity is enhanced when writing by hand compared to typing on a keyboard, which has implications for memory and learning, especially in classrooms.

Jan 27, 2024

Exercise’s Dopamine-Driven Cognitive Boost

Posted by in categories: biotech/medical, health, neuroscience

An exciting study reveals how exercise boosts brain power.


Summary: Recent research has revealed a significant link between exercise and improved cognitive performance, attributing this enhancement to increased dopamine levels. This discovery, involving sophisticated PET scans to monitor dopamine release in the brain during exercise, indicates that dopamine plays a vital role in boosting reaction times and overall brain function.

The study’s implications are far-reaching, suggesting potential therapeutic applications for conditions influenced by dopamine, like Parkinson’s disease and ADHD. The research underscores the importance of voluntary exercise for cognitive health, differentiating it from involuntary muscle stimulation.

Jan 26, 2024

New simulation tool advances molecular modeling of biomolecular condensates

Posted by in categories: biotech/medical, chemistry, neuroscience

A University of Massachusetts Amherst team has made a major advance toward modeling and understanding how intrinsically disordered proteins (IDPs) undergo spontaneous phase separation, an important mechanism of subcellular organization that underlies numerous biological functions and human diseases.

IDPs play crucial roles in cancer, neurodegenerative disorders and infectious diseases. They make up about one-third of proteins that human bodies produce, and two-thirds of cancer-associated proteins contain large, disordered segments or domains. Identifying the hidden features crucial to the functioning and self-assembly of IDPs will help researchers understand what goes awry with these features when diseases occur.

In a paper published in the Journal of the American Chemical Society, senior author Jianhan Chen, professor of chemistry, describes a novel way to simulate separations mediated by IDPs, an important process that has been difficult to study and describe.

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