Lifeboat Foundation

Scerri now knows when people dropped their tools on the barren ridge, but she can only speculate as to just who they were.

“The hominins responsible for the Acheulean at the site made their way into the heart of now arid Arabia by following lake and river channels. Once there, they climbed up the largest dyke, which was also a source of raw material,” she says. The toolmaking site they created there, perched at a lofty vantage point from which they could observe the surrounding plains, hints at how they may have thought and lived. “We don’t know which hominin taxon made these tools, but what we can say is that the hominins were resourceful and intelligent,” adds Scerri, of the Max Planck Institute and the University of Oxford.

Why these hominins took such a route at all is another area of intriguing speculation. “Although Arabia was wetter when these hominins were at Saffaqah, it was still a marginal environment,” Scerri says. “Were they pushed to the margins by larger brained hominins elsewhere, such as Neanderthals or even Homo sapiens in Africa?”

Continue reading “Stone Tools at Arabian ‘Crossroads’ Present Mysteries of Ancient Human Migration” »

Rosalinda Roberts had gotten used to seeing weird shapes in the brain. Over three decades of looking at brain tissue under an electron microscope, she’d regularly come across “unknown objects”—specks and blobs in her images that weren’t supposed to be there, and didn’t seem to relate to the synapses and structure that she was studying. “I’d just say, ‘well I’m not going to pay attention to that’” she explains. That’s all changed now.

Finding bacteria in the brain is usually very bad news. The brain is protected from the bacterial menagerie of the body by the blood-brain barrier, and is considered a sterile organ. When its borders are breached, things like encephalitis and meningitis can result. Which made it all the more surprising when Roberts, along with Charlene Farmer and Courtney Walker, realized that the unknown objects in their slides were bacteria.

Many of them were caught mid-stride, entering neurons or penetrating axons. Others were in the process of dividing. They were picky, too, strongly preferring some regions of the brain over others. The surrounding brain tissue showed no signs of inflammation. If the bacteria were in the brain while the individual was alive, they were not pathogenic.

Tau protein aggregation is associated with cellular senescence in the brain is the topic for the November Journal Club. This is an important paper as it shows how senescent cells contribute to Alzheimer’s disease and how removing them appears to improve the condition. We will see you live on our Facebook page at 13:00 EST for the Journal Club show with Dr. Oliver Medvedik.

Abstract

Tau protein accumulation is the most common pathology among degenerative brain diseases, including Alzheimer’s disease (AD), progressive supranuclear palsy (PSP), traumatic brain injury (TBI), and over twenty others.

Tracking brain wave activity in individuals at high risk for Alzheimer’s disease may be a promising new method for early detection, according to a new Canadian study by researchers at Baycrest Centre for Geriatric Care in Toronto, Ontario.

This is possible because brain waves tend to slow down in certain regions likely to be affected by the disease next, even before neurons have been lost.

The findings, published online in the journal Human Brain Mapping, show that individuals potentially in the early stages of Alzheimer’s disease (mild cognitive impairment) and those with a rare form of language dementia (primary progressive aphasia) exhibited sluggish brainwaves and subtle signs of damage in the brain regions responsible for memory and planning.

Continue reading “Sluggish Brain Waves May Be Early Sign of Dementia” »

All brain cells ‘air-kiss’ before they come together to form a final synaptic relationship, new research by University of Kent scientists has revealed.

The breakthrough study reveals that molecular signaling within the brain operates in a very different way to previously thought, with cells now found to use the same pair of molecules for both distant and close contacts.

The research, by a team led by Professor Yuri Ushkaryov of the University’s Medway School of Pharmacy, may lead to a much better understanding of how neurons send messages to distant parts of the brain or other organs in the body, such as muscle cells.

According to a study recently published by researchers at the University of Colorado, empathy is rooted in cognitive processes rather than sensory ones, as reported by the Daily Camera. The study found that the act of understanding the pain of others does not involve the same neural pathways as experiencing pain in one’s own body, suggesting that the two are different interactions within the brain.

The study revealed that the brain patterns of volunteers when they experienced pain themselves did not overlap with their brain patterns when the volunteers were observing the pain of others. When observing pain, the volunteers showed brain patterns consistent with “mentalizing,” which involves imagining another’s thoughts and intentions.

“The research suggests that empathy is a deliberative process that requires taking another person’s perspective rather than being an instinctive, automatic process,” said Tor Wager, the Director of the University of Colorado’s Cognitive and Affective Neuroscience Laboratory and the senior author of the study, as reported by Daily Camera.

Continue reading “Empathy Is Rooted In Cognitive Neural Processes Rather Than Sensory Ones” »

Our results suggest at least two different ways in which the brain has evolved to anticipate the future.

Go ahead and add ‘seeing the future’ to the growing list of amazing things your brain can do.

Well, almost, at least. According to new research from the University of California, Berkeley, it turns out that humans have the innate skill to somewhat predict or anticipate some things moments before they actually happen.

Continue reading “The human brain has two internal clocks that allow you to see the future, new research says” »

Already, it could help people express hunger or pain.

In a world first, a patient with Parkinson’s disease has undergone transplant therapy, which uses reprogrammed stem cells to replace neurons destroyed by the disease.

Stem cell therapy is part of the toolkit

The stem cell field is an area of science that is relatively well funded and, out of all the branches of medical science relevant to aging, is probably the most understood by the public. In the last decade or so, progress in stem cell research has been rapid, and scientists now have a wide range of cell types they can create on demand via cellular programming.

Continue reading “Parkinson’s Disease Patient in World First Stem Cell Therapy” »