Lifeboat Foundation

UCLA scientists working with middle-aged fruit flies say they were able to improve the insects’ health while markedly slowing down their aging process. The team thinks its technique could eventually help delay the onset of Parkinson’s disease, Alzheimer’s disease, cancer, stroke, cardiovascular disease, and other age-related diseases in humans.

The researchers zeroed in on mitochondria, which often become damaged with age. When cells can’t eliminate the damaged mitochondria, they can become toxic and contribute to a wide range of age-related diseases, said David Walker, Ph.D., a UCLA professor of integrative biology and physiology, and the study’s senior author.

Dr. Walker and his colleagues found that as fruit flies reach middle age—about one month into their two-month lifespan—their mitochondria change from their original small, round shape.

Continue reading “UCLA Team Genetically Manipulates Mitochondria to Extend Fruit Flies’ Lifespan” »

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Neuroscientists have used the application of sophisticated mathematics to peer into the structure of our brains. What they’ve discovered is that the brain contains multi-dimensional geometrical structures and spaces within the networks of our brains that operate in 11 dimensions.

We’re used to seeing the world in 3 dimensions, but this recent study is opening up new research into the brain and how we perceive reality.

Algebraic topology, popularly known as “rubber-sheet geometry”, is used to study different kinds of hole structures, and scientists say the research has significant implications for our understanding of the brain.

Continue reading “The human brain can create structures in up to 11 dimensions” »

Alison Sommer graduated from Carleton with a degree in Asian Studies, and now works as an academic technologist at Macalester College. She believes that awareness is the first step to improving problems within mental health care, and will be speaking about anxiety disorders and panic attacks based on her own constantly evolving understanding of her anxiety disorder, OCD. Alison’s greatest loves are her family, hockey and Star Wars.

My first goal here today is not to have a panic attack right on stage. I have an anxiety disorder called Obsessive Compulsive Disorder or OCD. Obsessive Compulsive…I have a form of Obsessive Compulsive Disorder that causes me to become anxious or frightened when something wrong or unexpected happens. Like if somebody sits at my seat at the table.

The secret to a long life? A protein that acts as a cellular ‘time machine’ is found to extend the lifespan of fruit flies by 20%.

Biologists have turned back the clock on ageing in the cells of fruit flies, by increasing levels of a protein called Drp1.

Continue reading “Cellular ‘time machine’ could offer Parkinson’s treatment” »

It has long been accepted that people and other primates are born with the ability to recognize faces; however, a new study at Harvard Medical School has brought that into question.

The study findings suggest that facial recognition is not innate but is learned

The new study published in Nature Neuroscience worked with macaques that had been temporarily prevented from seeing faces while growing up[1]. The researchers discovered that areas of the brain involved in facial recognition form due to experience and are not present in primates who do not see faces while they grow up. This brings into question the long-held idea that we are simply born with the ability to recognize faces.

Each of our human brains is special, carrying distinctive memories and giving rise to our unique thoughts and actions. Most research on the brain focuses on what makes one brain different from another. But recently, Allen Institute researchers turned the question around.

“So much research focuses on the variations between individuals, but we turned that question on its head to ask, what makes us similar?” says Ed Lein, Ph.D., Investigator at the Allen Institute for Brain Science. “What is the conserved element among all of us that must give rise to our unique cognitive abilities and human traits?”

Their work, published this month in Nature Neuroscience, looked at gene expression across the entire human brain and identified a surprisingly small set of molecular patterns that dominate gene expression in the human brain and appear to be common to all individuals.

Continue reading “Decoding the patterns that make our brains human” »

When Kristopher Boesen of Bakersfield regained consciousness after losing control of his car while driving in wet conditions, he was paralyzed from the neck down. The prognosis was grim: he was told that he might never regain control of his limbs again.

But he has. At least some of them. He has movement in his upper body and can use his arms and hands. He can feed himself, text friends and family and even hug them. To him, this means that he has his life back. How did this miracle come about?

Kris was offered the opportunity to participate in a human clinical trial at the University of Southern California and Asterias Biotherapeutics. He is one of five previously paralyzed patients who experienced increased mobility after the trial.

Continue reading “First paralyzed human regains his upper body movement after being treated with stem cells” »

If there was a poster child of aging diseases, it would be Alzheimer’s disease. The brains of people suffering from Alzheimer’s disease have deposits of amyloids resulting from the loss of proteostasis. Alzheimer’s disease is accompanied by the presence of amyloid beta protein and tau protein as well as large numbers of activated pro-inflammatory immune cells.

The debate about which is primary has raged for many years in the research world, and it is still not clear how these three elements combine to cause disease progression. A new study has attempted to untangle the mystery and suggests the order is beta amyloid, inflammation, then tau, and this study identifies new targets for therapies[1].