Lifeboat Foundation

Computational molecular physics (CMP) aims to leverage the laws of physics to understand not just static structures but also the motions and actions of biomolecules. Applying CMP to proteins has required either simplifying the physical models or running simulations that are shorter than the time scale of the biological activity. Brini et al. reviewed advances that are moving CMP to time scales that match biological events such as protein folding, ligand unbinding, and some conformational changes. They also highlight the role of blind competitions in driving the field forward. New methods such as deep learning approaches are likely to make CMP an increasingly powerful tool in describing proteins in action.

Science, this issue p.

### BACKGROUND

The biggest computer chip in the world is so fast and powerful it can predict future actions “faster than the laws of physics produce the same result.”

That’s according to a post by Cerebras Systems, a startup company that made the claim at the online SC20 supercomputing conference this week.

Working with the U.S. Department of Energy’s National Energy Technology Laboratory, Cerebras designed what it calls “the world’s most powerful AI compute system.” It created a massive chip 8.5 inch-square chip, the Cerebras CS-1, housed in a refrigerator-sized computer in an effort to improve on deep-learning training models.

The newly measured rate of a key nuclear fusion process that forged the first atomic nuclei matches the picture of the universe 380,000 years later.

Three physicists in the Department of Physics and Astronomy at the University of Tennessee, Knoxville, together with their colleagues from the Southern University of Science and Technology and Sun Yat-sen University in China, have successfully modified a semiconductor to create a superconductor.

Professor and Department Head Hanno Weitering, Associate Professor Steve Johnston, and PhD candidate Tyler Smith were part of the team that made the breakthrough in fundamental research, which may lead to unforeseen advancements in technology.

Semiconductors are electrical insulators but conduct electrical currents under special circumstances. They are an essential component in many of the electronic circuits used in everyday items including mobile phones, digital cameras, televisions, and computers.

Paging Philip Pullman.

Physicists have found a way to induce and cancel magnetic fields from a distance.

O,.o this reveals the hertz of the spacetime continuum: 3.

In the biggest events in the universe, massive black holes collide with a chirp and a ring. Physicists are finding ways to listen in.

It might be possible, physicists say, but not anytime soon. And there’s no guarantee that we humans will understand the result.

Trillion-transistor chip can run real-world simulations with over a million variables faster than real-time.