Lifeboat Foundation

Ellen Swallow Richards was not going to be intimidated by a room full of health experts and officials. Children were dying and their parents, Boston’s taxpayers, and city officials were to blame. The tiny, square-chinned woman thought nothing of climbing over boulders in petticoats, collecting thousands of water samples by horseback, or exploring mines on her honeymoon. So when she took the podium at the 1896 meeting of the American Public Health Association, she wasted no time in laying out her evidence.

More than 5,000 cases of illness could be attributed to the illegal conditions in Boston’s public schools, she said. Buildings lacked ventilation. Sewer pipes were still open. Toilets were filthy. Some 41 percent of the floors had never been washed. Only 27 of the city’s 168 schools had fire escapes that worked. Fully half of Boston’s schoolhouses were “deleterious to health.” The public and parents should be charged with “the murder of some 200 children per year,” Richards declared, their deaths entirely preventable from environmental hazards.

The strident, accusatory tone of Richards’ speech was remarkable, given how tactful she had been in the first two decades of her career. That tact had been a coping strategy, characteristic of a pragmatic feminism. Richards had been the first woman admitted to the Massachusetts Institute of Technology and the university’s first woman instructor. To blend in, she made a conscious effort to appear as unthreatening and feminine as she possibly could to her male colleagues. She even mended their clothes when they asked.

The de Grey… AEWR.

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People in Ethiopia did not live in low valleys during the last ice age. Instead they lived high up in the inhospitable Bale Mountains. There they had enough water, built tools out of obsidian and relied mainly on giant rodents for nourishment. This discovery was made by an international team of researchers led by Martin Luther University Halle-Wittenberg (MLU) in cooperation with the Universities of Cologne, Bern, Marburg, Addis Ababa and Rostock. In the current issue of “Science”, the researchers provide the first evidence that our African ancestors had already settled in the mountains during the Palaeolithic period, about 45,000 years ago.

At around 4,000 metres above sea level, the Bale Mountains in southern Ethiopia are a rather inhospitable region. There is a low level of oxygen in the air, temperatures fluctuate sharply, and it rains a lot. “Because of these adverse living conditions, it was previously assumed that humans settled in the Afro-Alpine region only very lately and for short periods of time,” says Professor Bruno Glaser, an expert in soil biogeochemistry at MLU. Together with an international team of archaeologists, soil scientists, palaeoecologists, and biologists, he has been able to show that this assumption is incorrect. People had already begun living for long periods of time on the ice-free plateaus of the Bale Mountains about 45,000 years ago during the Middle Pleistocene Epoch. By then the lower valleys were already too dry for survival.

For several years, the research team investigated a rocky outcrop near the settlement of Fincha Habera in the Bale Mountains in southern Ethiopia. During their field campaigns, the scientists found a number of stone artefacts, clay fragments and a glass bead. “We also extracted information from the soil as part of our subproject,” says Glaser. Based on the sediment deposits in the soil, the researchers from Halle were able to carry out extensive biomarker and nutrient analyses as well as radiocarbon dating and thus draw conclusions as to how many people lived in the region and when they lived there. For this work, the scientists also developed a new type of palaeothermometer which could be used to roughly track the weather in the region — including temperature, humidity and precipitation. Such analyses can only be done in natural areas with little contamination, otherwise the soil profile will have changed too much by more recent influences.

News & Media Website.

By Amy Woodyatt, CNN—Wed August 7, 2019

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For DeepMind, the emergence of the new headquarters is symbolic of a new chapter for the company as it turns its research heft and compute power to try to understand, among other things, the building blocks of organic life. In so doing, the company hopes to make breakthroughs in medicine and other disciplines that will significantly impact progress in a number of fields. “Our mission should be one of the most fascinating journeys in science,” Hassabis says. “We’re trying to build a cathedral to scientific endeavour.”

DeepMind’s AI has beaten chess grandmasters and Go champions. But founder and CEO Demis Hassabis now has his sights set on bigger, real-world problems that could change lives. First up: protein folding.

https://www.linkedin.com/pulse/current-state-longevity-scien…colangelo/

A paper posted online this month has settled a nearly 30-year-old conjecture about the structure of the fundamental building blocks of computer circuits. This “sensitivity” conjecture has stumped many of the most prominent computer scientists over the years, yet the new proof is so simple that one researcher summed it up in a single tweet.

“This conjecture has stood as one of the most frustrating and embarrassing open problems in all of combinatorics and theoretical computer science,” wrote Scott Aaronson of the University of Texas, Austin, in a blog post. “The list of people who tried to solve it and failed is like a who’s who of discrete math and theoretical computer science,” he added in an email.

The conjecture concerns Boolean functions, rules for transforming a string of input bits (0s and 1s) into a single output bit. One such rule is to output a 1 provided any of the input bits is 1, and a 0 otherwise; another rule is to output a 0 if the string has an even number of 1s, and a 1 otherwise. Every computer circuit is some combination of Boolean functions, making them “the bricks and mortar of whatever you’re doing in computer science,” said Rocco Servedio of Columbia University.

Two remarkable new studies are suggesting sci-fi stories of memory manipulation may not be so far-fetched. The research describes early proof-of-concept experiments showing how negative emotional associations with traumatic memories can potentially be weakened or even entirely edited out.