Also discussed is a comparison between analog computing and digital in the context of computational biology. In this video I am reading a recent discussion of my notes with Self Aware Networks.
James Earl Jones died Monday at the age of 93. But long before he did, he gave Lucasfilm permission to recreate his iconic Darth Vader voice for shows like “Obi-Wan Kenobi.”
Despite the initial excitement and flashy headlines, all of these early ventures failed or switched focus away from aging. Most of these companies and their backers underestimated the complexity, costs, and time it would take to discover and develop a drug. Recent estimates suggest that developing a new drug takes over https://www.sciencedirect.com/science/article/abs/pii/S1359644623002428” rel=“noopener”>10 years and costs upwards of $6.1 billion and the failure rates exceed 90%. This figure reflects the immense difficulty of identifying therapeutic targets, conducting preclinical and clinical trials, and navigating the regulatory landscape. When it comes to developing a drug specifically for aging, the challenges multiply, making it much more difficult to design effective interventions and demonstrate their efficacy in clinical trials.
Fast forward to today, and a new generation of longevity biotechnology companies with a more conservative approach than their predecessors has emerged. Companies like http://www.bioagelabs.com” rel=“noopener”>BioAge Labs and http://www.insilico.com” rel=“noopener”>Insilico Medicine are using artificial intelligence (AI) to discover drugs that target specific chronic diseases or biological processes closely associated with aging. Instead of trying to develop therapies for aging directly, these companies focus on conditions that are closely linked to the aging process like obesity, muscle wasting, fibrosis, anemia, and even cancer… The strategy is to develop drugs for these diseases that could later be repurposed to address aging more broadly. And while in the technology industry we try to focus on moving very fast to win, here we prepare to play a very long game and focus on resilience and novelty rather than putting all eggs in one basket and failing miserably like dozens of companies in the past three decades.
Researchers have developed a technique using DNA microbeads to control organoid development. This method releases growth factors and signal molecules precisely, creating more complex and realistic organoids.
A new study from the University of Copenhagen reveals that a specific gene plays a significant role in determining longevity, potentially opening the door to new treatments.
Sleep, fasting, exercise, green porridge, black coffee, a healthy social life…
There is an abundance of advice out there on how to live a good, long life. Researchers are working hard to determine why some people live longer than others, and how we get the most out of our increasingly long lives.
Live coverage from NASA’s Kennedy Space Center as the Polaris Dawn crew launches on a mission to perform the world’s first commercial space walk. Liftoff from pad 39A, atop a Falcon 9 rocket, is scheduled for no earlier than Tuesday, September 10, 2024 at 3:38 a.m. EDT (0738 UTC).
Aboard Dragon Resilience are mission commander, Jared Isaacman, retired U.S. Air Force pilot, Scott “Kidd” Poteet, and two SpaceX Lead Space Operations Engineers, Anna Menon and Sarah Gillis. In addition to performing the spacewalk the crew will fly further from Earth than anyone since the Apollo era.
A research team has identified key visual perceptual factors that enhance the viewing experience of 3D displays.
The research revealed that the presence of parallax significantly impacts the perceived realism and immersion of 3D images viewed through holographic displays.
The results of this study were published in ACM Transactions on Graphics on July 19, and were presented at the international conference on computer graphics, SIGGRAPH 2024, held in Denver from July 28 to August 1.
Hyperloop, a new form of mass transit involving capsules whizzing on magnetic fields through depressurized tubes, has achieved significant liftoff in the northern Netherlands, a company developing the technology said Monday.
A test vehicle was levitated and zipped through a tube at a testing facility for the high-speed transit system once promoted by Elon Musk.
“So today, with the first successful test, we were able to levitate the vehicle, also turn on the guidance system and the propulsion system,” Marinus van der Meijs, the technology and engineering director at hyperloop company Hardt, told The Associated Press late last week before Monday’s formal announcement.
A virtual haptic implementation technology that allows all users to experience the same tactile sensation has been developed. A research team led by Professor Park Jang-Ung from the Center for Nanomedicine within the Institute for Basic Science (IBS) and Professor Jung Hyun Ho from Severance Hospital’s Department of Neurosurgery has developed a technology that provides consistent tactile sensations on displays.
This research was conducted in collaboration with colleagues from Yonsei University Severance Hospital. It was published in Nature Communications on August 21, 2024.
Virtual haptic implementation technology, also known as tactile rendering technology, refers to the methods and systems that simulate the sense of touch in a virtual environment. This technology aims to create the sensation of physical contact with virtual objects, enabling users to feel textures, shapes, and forces as if they were interacting with real-world items, even though the objects are digital.
A new, cheap, easily manufactured device could lead to improved satellite communication, high speed data transmission, and remote sensing, scientists say.
A team of engineers led by researchers from the University of Glasgow have developed an ultrathin 2D surface that harnesses the unique properties of metamaterials to manipulate and convert radio waves across the frequencies most commonly used by satellites.
Metamaterials are structures that have been carefully engineered to imbue them with properties that don’t exist in naturally occurring materials.
