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A molecular biology research team at the University of Miami Miller School of Medicine has become the first to map out how mitochondrial messenger RNA folds in human cells.

The research advances knowledge about the expression of genes in the mitochondria and paves the way for identification of therapeutic targets for mitochondrial neurodegenerative diseases.

“Dysfunctional mitochondria can cause devastating diseases, frequently with childhood-onset, known as mitochondrial encephalomyopathies. Despite advances in identifying genes responsible for these disorders, their pathophysiological mechanisms have been poorly understood,” said Antoni Barrientos, Ph.D., professor of neurology and biochemistry and molecular biology at the Miller School. “This was partly due to a lack of a full understanding of mitochondrial gene expression. Specifically, nothing was known about how mitochondrial messenger RNA folds and how that could influence its stability and translation in health and disease.”

PDF Host read free online — Epiphenomenalism.

To produce light, lasers typically rely on optical cavities, pairs of mirrors facing each other that amplify light by bouncing it back and forth. Recently, some physicists have been investigating the generation of “laser light” in open air without the use of optical cavities, a phenomenon known as cavity-free lasing in atmospheric air.

SpaceX finished construction of its second launch tower down at Starbase, Texas for its Starship rocket. This comes hopefully a few weeks out from the next launch of the company’s next generation rocket.

Over the last few months SpaceX has cleared land and constructed a new launch tower at its research, development, and launch facilities down at Starbase, Texas. This now gives the company three towers total for Starship, two at Starbase and one more over in Florida at LC-39A.

There is still plenty of work to be done at the pad, it still needs the launch table, chopsticks, plumbing for propellent, etc. However, the biggest and most prominent feature is now complete.

I’ll never not see Neuralink as some kind of sorcery.

The next step, says Esat, is to increase the new device’s magnetic field sensitivity by implementing more advanced sensing protocols based on pulsed electron spin resonance schemes and by finding molecules with longer spin decoherence times. “We hope to increase the sensitivity by a factor of about 1,000, which would allow us to detect nuclear spins at the atomic scale,” he says.

A holy grail for quantum sensing

The new atomic-scale quantum magnetic field sensor should also make it possible to resolve spins in certain emerging two-dimensional quantum materials. These materials are predicted to have many complex magnetic orders, but they cannot be measured with existing instruments, Heinrich and his QNS colleague Yujeong Bae note. Another possibility would be to use the sensor to study so-called encapsulated spin systems such as endohedral-fullerenes, which comprise a magnetic core surrounded by an inert carbon cage.

Built by Natron Energy, the Edgecombe County facility is planned for 24 GWh of annual capacity, which would turn Natron from a startup into the first sodium-ion battery production juggernaut on US soil.

Sodium-ion batteries are cheaper, safer, with much longer lifespan and faster charging than conventional Li-ion packs.

Chinese companies are already using them in grid-level energy storage systems of local utilities, to balance their renewable energy mix. Some sodium-ion battery packs are even making their way into electric vehicles there, even though the chemistry offers lower energy density than Li-ion batteries.

In an era where AI is reshaping industries at breakneck speed, Doug Seven finds himself at the forefront of a technology that’s changing the way developers approach their work.

As the director and general manager of AWS AI Developer Experiences, Seven is at the helm of this transformation, where specialized AI is not just assisting but actively reshaping how code is written and deployed.

Continue reading “AWS exec explains how AI agents are driving a radical shift in the world of coding” »

U.S. Naval Research Laboratory (NRL) scientists confirm the identification of a new class of semiconductor nanocrystals with bright ground-state excitons, a significant advancement in the field of optoelectronics, in an article published in the American Chemical Society (ACS) journal ACS Nano.

The groundbreaking theoretical research could revolutionize the development of highly efficient light-emitting devices and other technologies.

Generally, the lowest-energy exciton in nanocrystals is poorly emitting, earning the name “dark” exciton. Because it slows the emission of light, the dark exciton limits the performance of nanocrystal-based devices like lasers or light-emitting diodes (LEDs). Scientists have long sought to overcome the dark exciton.