Lifeboat Foundation

Interim Intel co-CEO Michelle Johnston Holthaus announced that the first engineering samples of hardware manufactured with the company’s 18A semiconductor node have been delivered to customers. Her comments aim to reassure industry observers that Intel’s foundry business remains on track to compete with TSMC’s and Samsung’s 3nm and 2nm nodes starting next year.

At the Barclays Annual Global Technology Conference, Holthaus and co-CEO David Zinsner discussed Intel’s upcoming Panther Lake processors, which will debut the 18A process node upon their expected launch in the second half of 2025. Holthaus revealed that eight foundry customers have powered on ES0 (likely “Engineering Sample 0”) chips built on the 18A node, signaling significant progress compared to six months ago.

Intel released version 1.0 of the 18A process design kit in July, enabling customers to begin developing chips based on the node. In August, the company confirmed that internal samples of Panther Lake and Clearwater Forest processors, built on the 18A node, successfully powered on and booted Windows with satisfactory performance. The statements made at the Barclays event mark the first confirmation of 18A usage outside of Intel.

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Summary: Researchers have identified a genetic mechanism that regulates behavioral adaptations to emotional experiences by forming R-loops, unique RNA: DNA structures that activate target genes. The study focused on NPAS4, a gene implicated in stress and drug addiction, showing how blocking R-loops prevents maladaptive behaviors like cocaine seeking and stress-induced anhedonia in mice.

This mechanism demonstrates how emotional experiences influence brain circuits by altering gene expression through enhancer RNA. The findings could pave the way for RNA-based therapies to treat psychiatric disorders linked to stress and substance use.

Conquering space is among the main challenges humanity now has — and the huge number of discoveries made in recent decades suggests that nothing is impossible. Tourism beyond Earth is already gaining popularity, and this sector will evolve soon. However, simply enjoying the space views may become boring shortly, and travellers will search for alternative entertainment options. It’s now pretty early to ask whether people will be able to build a land-based casino on the Moon, but some experiences may become available in the near future. The iGaming sector is rapidly evolving, leaving offline settings behind. We can predict that space gambling will begin from top-rated slot games not on GamStop, which are widely accessible globally. Casino platforms have a vast growth potential nowadays, so what would prevent people from using them when enjoying space tourism?

The first bet beyond the Earth has already been placed — this significant event happened in 2021 when Jared Isaacman, the Inspiration 4x commander, wagered on the NFL. Although it may take a while for such betting experiences to become more widespread, the beginning has already been made.

Some say OpenAI’s o1 models are close to artificial general intelligence.

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Gravity is a fascinating force, it’s what holds everything on our planet together, and it might one day help us travel to other planets.

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What is time? Is it just a ticking clock, or is it something more profound?

Continue reading “What is Time? Stephen Wolfram’s Groundbreaking New Theory [Ep. 468]” »

Trying to stay healthy into old age is a better goal than attempting to live as long as possible.

Is your skin itching, breaking out, or acting weird? Not sure what’s causing those problems? Get an overview of symptoms and types of skin conditions.