Lifeboat Foundation: Safeguarding Humanity
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Blog – Page 81

Veeam has patched a critical remote code execution vulnerability tracked as CVE-2025–23120 in its Backup & Replication software that impacts domain-joined installations.

The flaw was disclosed yesterday and affects Veeam Backup & Replication version 12.3.0.310 and all earlier version 12 builds. The company fixed it in version 12.3.1 (build 12.3.1.1139), which was released yesterday.

According to a technical writeup by watchTowr Labs, who discovered the bug, CVE-2025–23120 is a deserialization vulnerability in the Veeam. Backup. EsxManager.xmlFrameworkDs and Veeam.Backup.Core. BackupSummary. NET classes.

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Two malicious VSCode Marketplace extensions were found deploying in-development ransomware, exposing critical gaps in Microsoft’s review process.

The extensions, named “ahban.shiba” and “ahban.cychelloworld,” were downloaded seven and eight times, respectively, before they were eventually removed from the store.

It is notable that the extensions were uploaded onto the VSCode Marketplace on October 27, 2024 (ahban.cychelloworld) and February 17, 2025 (ahban.shiba), bypassing safety review processes and remaining on Microsoft’s store for an extensive period of time.

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A team of researchers at Peking University claims to have made a breakthrough in chip technology, potentially reshaping the semiconductor race.

Their newly developed 2D transistor is said to be 40% faster than the latest 3-nanometre silicon chips from Intel and TSMC while consuming 10% less energy. This innovation, they say, could allow China to bypass the challenges of silicon-based chipmaking entirely.

“It is the fastest, most efficient transistor ever,” according to an official statement published last week on the PKU website.

Led by physical chemistry professor Peng Hailin, the research team believes their approach represents a fundamental shift in semiconductor technology.

Peking University researchers have developed a 2D transistor that operates 40% faster and uses 10% less energy than leading silicon chips.

Continue reading “China’s ‘fastest-ever’ 2D chip beats Intel with 40% more speed” | >

Rabah et al. discover an astrocyte-to-neuron hydrogen peroxide signalling cascade, which is crucial for long-term memory formation in Drosophila. This signalling is found to be inhibited by amyloid-β peptide, suggesting a link to Alzheimer’s disease.

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Mechanism of neuroinflammation protection by astrocytes.

How astrocytes controls neuroinflammation is not clearly understood.

The researchers demonstrate that the upregulation of basic leucine zipper ATF-like transcription factor (BATF)2 downstream of IFNg regulates the inflammatory potential of astrocytes during neuroinflammation.

In vivo evidence suggests that BATF2 limits CNS autoimmunity and the expression of IFNg-driven inflammatory mediators.

Mechanistically, BATF2 binds and prevents the overexpression of IFN regulatory factor (IRF)1 and IRF1 targets such as caspase-1. Batf2−/− mice exhibit exacerbated clinical disease severity in a murine model of central nervous system autoimmunity and express increased astrocyte-specific IRF1 and caspase-1, suggesting an amplified IFN response in vivo.

They also demonstrate that BATF2 expressed primarily in astrocytes within multiple sclerosis lesions and that this expression is colocalized with IRF1.

These data suggest that BATF2 contributes to protective mechanisms in astrocytes during chronic neuroinflammation. https://sciencemission.com/BATF2-and-neuroinflammation

Continue reading “BATF2 is a regulator of interferon-γ signaling in astrocytes during neuroinflammation” | >

Here Harkos et al. review the role of continuous models and discrete models in predicting and understanding therapy delivery and efficacy in solid tumours. They propose ways to integrate mechanistic and AI-based models to further improve patient outcomes.

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