Lifeboat Foundation

This is part of our ongoing series of articles that discuss the Hallmarks of Aging. Published in 2013, the paper divides aging into distinct categories (“hallmarks”) of damage to explain how the aging process works and how it causes age-related diseases. Today, we will be looking at the hallmark of cellular senescence.

What are senescent cells?

As you age, increasing numbers of your cells enter into a state known as senescence. Senescent cells do not divide or support the tissues of which they are part; instead, they emit a range of potentially harmful chemical signals that encourage nearby healthy cells to enter the same senescent state. Their presence causes many problems: they reduce tissue repair, increase chronic inflammation, and can even eventually raise the risk of cancer and other age-related diseases.

Pope Francis has declared the death penalty ‘inadmissible’ for Catholics.

After years of vehicle development and building anticipation, NASA has now put the crew in commercial crew spacecraft. The space agency announced the nine men and women who will be the first to fly on new spacecraft operated by Boeing and SpaceX.

Like a team in a science fiction movie, the six-lab squad funded by a 2017 MEDx Biomedical research grant is striking in its combination of diverse skills and duties.

The project is led by Kafui Dzirasa, MD’09, Ph.D.’07, HS’10-’16, associate professor of psychiatry and behavioral sciences and assistant professor in neurobiology and neurosurgery; and Nenad Bursac, Ph.D., professor of biomedical engineering and associate professor in medicine. Their team includes: Marc Caron, Ph.D., James B. Duke Professor of Cell Biology, professor in neurobiology and medicine; Fan Wang, Ph.D., professor of neurobiology; Christopher Kontos, MD, HS’93-’97, professor of medicine and associate professor of pharmacology and cancer biology—all at Duke University School of Medicine—and Jennie Leach, Ph.D., associate professor of chemical, biochemical, and environmental engineering at the University of Maryland Baltimore County, along with a cadre of committed graduate students, postdocs, and technicians.

Dzirasa’s background in engineering informs his approach to the study of neuropsychiatric illness and disease. In the summer of 2016, he and members of his lab were discussing the challenge of precisely monitoring brain activity.

Almost everyone who eats fast food is familiar with the frustration of trying to squeeze every last drop of ketchup out of the small packets that accompany french fries.

What most consumers don’t realize, however, is that food left behind in plastic packaging is not simply a nuisance. It also contributes to the millions of pounds of perfectly edible food that Americans throw out every year. These small, incremental amounts of sticky foods like condiments, dairy products, beverages, and some meat products that remain trapped in their packaging can add up to big numbers over time, even for a single household.

New research from Virginia Tech aims to cut down on that waste – and consumer frustration – with a novel approach to creating super slippery industrial packaging. The study, which was published in Scientific Reports and has yielded a provisional patent, establishes a method for wicking chemically compatible vegetable oils into the surfaces of common extruded plastics.

Continue reading “New approach to super slippery packaging aims to cut down on food waste” »

A team of researchers from Cologne and New York has presented proposals for future traffic management. A dynamic, fair toll for road use could reduce congestion.

In the current issue of Nature, the economists Peter Cramton, Axel Ockenfels (both University of Cologne) and Richard Geddes (Cornell University) describe a concept in which drivers would have to pay a dynamic fee for the use of roads. This would contribute to avoiding traffic jams and protecting the environment, the researchers argue. Fees that respond to traffic volumes in real time and with site precision, taking into account factors such as vehicle type and exhaust emissions, can significantly improve traffic flow and contribute to reducing air pollution.

Traffic jams are not only annoying and time-consuming, they are also costly. In Germany, the economic damage caused by congested roads in 2017 totaled approximately €80 billion. “Currently, road users who cause traffic jams, while damaging the environment and even incurring costs, are paying just as much as those who are not involved,” says Ockenfels. “Without a toll, this means that the general public is subsidizing these road users. That’s unfair.” A toll for road use would bring these costs to light and reduce congestion. “If the fee adapts to the volume of traffic and the situation on the road in real time, i.e., is more expensive at rush hour than around noon, everyone can choose the route that suits them best. This already works for navigation systems,” explains Cramton. “Ultimately, this would reduce the load on main traffic arteries, improve traffic flow and reduce CO₂ emissions.

https://paper.li/e-1437691924#/

Stefan Lorenz Sorgner, Ph.D. is a German metahumanist philosopher, Nietzsche scholar, philosopher of music, and an authority in the field of ethics of emerging technologies.

Stefan teaches philosophy at John Cabot University in Rome and is director and cofounder of the Beyond Humanism Network, Fellow at the Institute for Ethics and Emerging Technologies (IEET), Research Fellow at the Ewha Institute for the Humanities at Ewha Womans University in Seoul, and Visiting Fellow at the Ethics Centre of the Friedrich-Schiller-University in Jena, where he was also Visiting Professor during the Summer of 2016. He is also Editor-in-Chief of the Journal of Posthuman Studies.

Continue reading “Professor Stefan Lorenz Sorgner” »

https://paper.li/e-1437691924…

The term “transhumanism” was coined by Aldous Huxley’s brother, Julian, the evolutionary biologist and First Director-General of UNESCO founded 1954 London, now in Paris, Julian Huxley (1887–1975): “I believe in transhumanism: once there are enough people who can truly say that, the human species will be on the threshold of a new kind of existence, as different from ours as ours is from that of Peking man. It will at last be consciously fulfilling its real destiny.” (“Transhumanism.” Julian Huxley. In New Bottles for New Wine, pp 13–17. London: Chatto & Windus, 1957). https://www.newstatesman.com/2017/10/heritage-wars-politics-…out-unesco

The idea was developed by futurist FM 2030 was formerly known as F M Esfandiary, who taught in NY from 1966. “The contemporary meaning of the term “transhumanism” was foreshadowed by one of the first professors of futurology, FM-2030, who taught “new concepts of the human” at The New School in the 1960s, when he began to identify people who adopt technologies, lifestyles and worldviews “transitional” to posthumanity as “transhuman”. The Transhuman phase began with the Industrial Revolution, and in the Anthopocene era of today, many of us (especially in the West) have already progressed beyond the human (agricultural) stage, past the ‘transhuman’ Industrial era, to enjoy our current C21st posthuman post-industrial lifestyles.

Continue reading “Welcome to Posthuman wiki” »

We’re excited to announce that we have partnered with Future Grind to produce the Rejuvenation Roundup Podcast, hosted by Ryan O’Shea! Explore the latest in life extension and anti-aging science with a dive into a month’s worth of scientific insights and new breakthroughs. More at lifespan.io/roundup