Lifeboat Foundation

The question and answer interview of He Jianku conference presentation has the most interesting parts of this debate about human gene editing of embryos. The interview starts at about 1 hour and 28 minutes of the record. The formal presentation showed that the scientist He has taken appropriate scientific care to perform the work. He took care to make sure it was on target and was successful. He took care to make sure there were no unintended off-target side-effects.

* the parents (father HIV positive) made a choice to use the edited embryos versus unedited * the CRISPR vector used to make the change. Appears to be the kind that can be ordered for about $100. There have been adult people who have self-experimented with mail order gene editing kits * the conference interviewer asked about whether He Jianku was aware of a few other research papers. Some paper suggests that the gene CCR5 could cause increased susceptibility to flu and another suggests a tiny increase in cognitive effect.

Continue reading “Theoretically Possibility That Gene Edited Twins Received a Tiny Intelligence Enhancement” »

The first-ever 8K broadcast has officially occurred, but don’t expect immediate uptake.

This simple statistic captures the power of the exponential growth in science that has been taking place over the past century. It is attributable to Derek de Solla Price, the father of scientometrics (i.e., the science of studying science), in his 1961 book Science Since Babylon. If science is growing exponentially, then the major technological advancements and upheavals of the past 200 years are only the tip of the iceberg.

Imagine one drug that can target and kill malignant cells for some patients with many types of cancer. A new drug called Vitrakvi (larotrectinib), now approved by the U.S. Food and Drug Administration, shows promise of doing just that for both adults and children with a variety of sometimes rare cancers that share one specific genetic mutation.

The mutation, called a TRK fusion, occurs when one of three NTRK genes becomes mistakenly connected to an unrelated gene and ignites uncontrolled growth. By solely targeting this mutation, the drug is designed to turn off growth signaling with a minimum of other toxicities.

According to the drug manufacturer, Loxo Oncology, this specific mutation can occur in a small subset of various adult and pediatric solid tumors ranging from cancers of the appendix, bile ducts, breast, lung, pancreas and thyroid to melanoma, GIST and various sarcomas.

Continue reading “FDA Approves Drug That Targets Key Genetic Driver of Cancer” »

A number of different things have to happen for a child to develop leukemia.

A massive, previously unexplored cave discovered by accident in Canada has been named “Sarlacc’s Pit,” after the multi-tentacled alien beast that first made an appearance in Star Wars: Return of the Jedi.

Officials from Canada’s Ministry of Environment and Climate Change first came across the huge cavern in Wells Gray Provincial Park in British Columbia while conducting a caribou count by helicopter in March.

Continue reading “Massive Cave Discovered in Canada, Named After ‘Star Wars’ Beast” »

Inspired by the insulation on a humble electrical cable, researchers have found that tiny ceramic particles can make plastic-backed cladding fire-safe.

How do you make a light-weight cladding material that doesn’t catch fire? It’s a question the building industry globally is wrestling with in the wake of the 2017 Grenfell Tower blaze in London that cost the lives of 72 people.

But according to new research, the answer is under your desk in the plastic insulation around the electrical cable powering your computer.

The promise of quantum computing brings with it some mind-blowing potential, but it also carries a new set of risks, scientists are warning.

Specifically, the enormous power of the tech could be used to crack the best cyber security we currently have in place.

A new report on the “progress and prospects” of quantum computing put together by the National Academies of Sciences, Engineering, and Medicine (NASEM) in the US says that work should start now on putting together algorithms to beat the bad guys.

Continue reading “We Need to Prepare For Quantum Attacks Now, Top US Scientists Warn” »

BepiColombo has fired its ion drives in preparation for Mercury orbital injection over the next seven years.