Lifeboat Foundation

The human eye is a remarkably sophisticated organ and like the lens to a camera, it’s the cornea that focuses the flood of photons into a perceptible image. But for an estimated 15 million people around the world, eye disease and trauma make surgery the only path to clear vision.

In the next few years, artificial corneas may become more accessible thanks to new research out of Newcastle University in the United Kingdom. There, researchers mixed stem cells from the cornea of a healthy donor with collagen and algae molecules to create a bio-ink, which they 3D-printed into an artificial cornea. The research is currently just a proof-of-concept but lays the groundwork for future techniques to create low-cost, easy-to-produce bionic eyes.

Continue reading “World’s first 3D-printed cornea made from algae and human stem cells” »

LEAF’s monthly roundup for May is out!

Summer is coming, and, albeit on a slightly longer timeframe, so is a world free of aging! So, grab an iced drink, sit comfortably on your beach chair, and let’s have a look together at some of the latest rejuvenation news.

The first LEAF conference in NYC is coming!

Continue reading “Rejuvenation Roundup May 2018” »

Not familiar with residential geothermal heating? No surprise. Chris Martin in Bloomberg explained that “Residential geothermal heating is uncommon, in part because the expense and effort to dig the wells make them costly to install in existing homes.”

Dandelion CEO Kathy Hannun told CNNMoney that “It’s a very niche technology that hasn’t taken off at all in this country.” Her Brooklyn-based company, Dandelion, is out there to make geothermal heating—extracting underground heat to keep homes warm— more affordable for homeowners.

On Wednesday, Dandelion launched the Dandelion Air as a home heating and air conditioning system. Dandelion’s claims: it’s 4 times more efficient than any furnace on the market and almost twice as efficient as a conventional air conditioning system. So, when you go up to Dandelion’s web site there is one sole message and it reads loud and clear. “Geothermal heating and air conditioning so efficient it pays for itself.”

Continue reading “Dandelion wants to play a role in home geothermal” »

Fuel cells and batteries provide electricity by generating and coaxing positively charged ions from a positive to a negative terminal which frees negatively charged electrons to power cellphones, cars, satellites, or whatever else they are connected to. A critical part of these devices is the barrier between these terminals, which must be separated for electricity to flow.

Improvements to that barrier, known as an electrolyte, are needed to make energy storage devices thinner, more efficient, safer, and faster to recharge. Commonly used liquid electrolytes are bulky and prone to shorts, and can present a fire or explosion risk if they’re punctured.

Research led by University of Pennsylvania engineers suggests a different way forward: a new and versatile kind of solid polymer electrolyte (SPE) that has twice the proton conductivity of the current state-of-the-art material. Such SPEs are currently found in proton-exchange membrane fuel cells, but the researchers’ new design could also be adapted to work for the lithium-ion or sodium-ion batteries found in consumer electronics.

Continue reading “Engineers design new solid polymer electrolyte, paving way for safer, smaller batteries and fuel cells” »

With the ability to be coaxed into different kinds of mature cell types, induced pluripotent stem cells (iPSCs) hold all kinds of potential in the world of regenerative medicine. One of the many possibilities could be repairing damaged hearts, something that will soon be put to the test for the first time ever in newly approved clinical trials in Japan.

Since emerging from the laboratory of researcher Shinya Yamanaka in Japan in 2006, the potential of iPSCs has been explored in all kinds of promising research efforts. We have seen them implanted into rabbits to restore their vision, become brain tumor predators, and turned into precursor cells for human organs.

IPSCs are created by first harvesting cells from body tissues and then infecting them with a virus, in turn introducing them to carefully selected genes that return them to their immature state. From there they can develop into any cell in the body, a capability so powerful it earned Yamanaka a Nobel Prize in 2012.

On Thursday, an international team of scientists announced a new explanation for the evolution of brain size expansion: Unique genes that, to date, have only been found in humans. They’re called NOTCHN2NL genes and so far the scientists have identified eight different versions of them.

Researchers at Queen Mary University of London have developed a new way to grow mineralised materials which could regenerate hard tissues such as dental enamel and bone.

Enamel, located on the outer part of our teeth, is the hardest tissue in the body and enables our teeth to function for a large part of our lifetime despite biting forces, exposure to acidic foods and drinks and extreme temperatures. This remarkable performance results from its highly organised structure.

However, unlike other tissues of the body, enamel cannot regenerate once it is lost, which can lead to pain and tooth loss. These problems affect more than 50 per cent of the world’s population and so finding ways to recreate enamel has long been a major need in dentistry.

Continue reading “Scientists develop material that could regenerate dental enamel” »

SpaceX CEO Elon Musk has responded to Boeing CEO Dennis Muilenburg’s comments on whether his company, working in collaboration with NASA, could reach Mars first. The pair have ratcheted up the competition, with plans to test the BFR and Space Launch System next year.

Forget zombies or killer robots – the most likely doomsday scenario in the near future is the threat of superbugs. Bacteria are evolving resistance to our best antibiotics at an alarming rate, so developing new ones is a crucial area of study. Now, inspired by a natural molecule produced by marine microorganisms, researchers at North Carolina State University have synthesized a new compound that shows promising antibacterial properties against resistant bugs.

Decades of overuse and overprescription of antibiotics has led to more and more bacteria becoming resistant to them, and the situation is so dire that a recent report warned that they could be killing up to 10 million people a year by 2050. Worse still, the bugs seem to be on schedule, with the ECDC reporting that our last line of defense has already begun to fail in large numbers.