Lifeboat Foundation

Researchers at the University of Virginia School of Medicine have discovered that as we age, our cells’ nuclear membranes become misshapen, which stops our genes from working properly.

Nuclear membranes become distorted with age

The DNA in all our cells is the same; however, the cells in our body show a great range of variation and function. How can this be when they have the same DNA? It all comes down to gene expression and which genes are turned off and which are turned on. For example, certain genes must be turned on in a cell for it to be a liver cell; those same genes need to be turned off for it to be a brain cell. If the correct genes are not turned off, problems occur.

Continue reading “Age-Related Changes to the Nuclear Membrane Alter Gene Expression” »

In case you missed it, Elon Musk called BS on the field of nanotechnology last week. The ensuing Twitter spat was admittedly rather small on the grand scale of things.

But it did throw up an important question: just what is nanotech, and where does the BS end and the science begin?

I have a sneaky suspicion that Musk was trolling with his initial nano-comment. After all, much of the tech in his cars, solar cells and rockets relies on nanoscale science and engineering.

Continue reading “Elon Musk Called Nanotechnology BS” »

As humans spread out into the cosmos in search of life, the most alien organisms we encounter may be those we bring with us. Researchers at NASA and elsewhere are engineering microbes so they can carry out many of the functions needed to support human life off-planet.

Humans have been harnessing microbes to do useful work for us for millennia. We’ve used them to make bread, beer, and cheese, and more recently they’ve been put to work to produce medicine, provide fertilizer for crops, and even generate biofuels.

But the emerging field of synthetic biology holds the promise of greatly expanding the things microbes can do for us. Advances in gene editing technology are allowing scientist to re – engineer microbes’ genomes to carry out entirely novel functions like producing chemicals not found in nature, acting as biosensors, and even carrying out computation.

Continue reading “Microbes in Space: Bioengineered Bugs Could Help Colonize New Planets” »

By the end of 2022, China hopes to have its biggest space station yet orbiting around Earth, and the country’s space agency wants other nations to use it. China is inviting all members of the United Nations to submit applications to fly experiments on board the future habitat, dubbed the China Space Station. It’s a major step toward international cooperation for China and its space program, which has mostly relied on domestic hardware and capabilities in the past.

“The China Space Station belongs not only to China, but also to the world,” Shi Zhongjun, China’s ambassador to the UN, said in a statement about the initiative. As a guide for the decision, Zhongjun cited the 50-year-old Outer Space Treaty, which maintains that the exploration of space should be peaceful and benefit all countries.

I will illustrate the massive game-changer that the SpaceX BFR will be. I will show this by describing how we can have millions of people in space by the 2040s.

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Norway’s electric vehicle adoption rate is so far ahead of most countries that it gives us glimpses into the future of bigger markets – sometimes even decades ahead of time.

Now it is starting to show signs of demand for gasoline and diesel slowing down as electric vehicles are taking over.

This weed-pulling robot is cheaper and better for the environment.

Nearsightedness, or myopia, is an increasing problem around the world. There are now twice as many people in the US and Europe with this condition as there were 50 years ago. In East Asia, 70 to 90 percent of teenagers and young adults are nearsighted. By some estimates, about 2.5 billion of people across the globe may be affected by myopia by 2020.

Eye glasses and contact lenses are simple solutions; a more permanent one is corneal refractive surgery. But, while vision correction surgery has a relatively high success rate, it is an invasive procedure, subject to post-surgical complications, and in rare cases permanent vision loss. In addition, laser-assisted vision correction surgeries such as laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) still use ablative technology, which can thin and in some cases weaken the cornea.

Columbia Engineering researcher Sinisa Vukelic has developed a new non-invasive approach to permanently correct vision that shows great promise in preclinical models. His method uses a femtosecond oscillator, an ultrafast laser that delivers pulses of very low energy at high repetition rate, for selective and localized alteration of the biochemical and biomechanical properties of corneal tissue. The technique, which changes the tissue’s macroscopic geometry, is non-surgical and has fewer side effects and limitations than those seen in refractive surgeries. For instance, patients with thin corneas, dry eyes, and other abnormalities cannot undergo refractive surgery. The study, which could lead to treatment for myopia, hyperopia, astigmatism, and irregular astigmatism, was published May 14 in Nature Photonics.