Lifeboat Foundation

Imec, the world-leading research and innovation hub in nano-electronics and digital technologies, presents this week at its technology forum ITF 2018 (Antwerp, May 23–24), a novel organ-on-chip platform for pharmacological studies with unprecedented signal quality. It fuses imec’s high-density multi-electrode array (MEA)-chip with a microfluidic well plate, developed in collaboration with Micronit Microtechnologies, in which cells can be cultured, providing an environment that mimics human physiology. Capable of performing multiple tests in parallel, the new device aims to be a game-changer for the pharmaceutical industry, offering high quality data in the drug development process.

Every year a handful of new drugs make it to the market, but in their wake tens of thousands of candidate drugs didn’t make the cut. Nevertheless, this journey will have taken a decade and costs billions. The fact that drug development is so time-consuming and costly, is because of the insufficiency of the existing methodologies for drug screening assays. These current assays are based on poor cell models that limit the quality of the resulting data, and result in inadequate biological relevance. Additionally, there is a lack of spatial resolution of the assays, resulting in the inability to screen single cells in a cell culture. Imec’s novel organ-on-chip platform aims to address these shortcomings and challenges.

Imec’s solution packs 16,384 electrodes, distributed over 16 wells, and offers multiparametric analysis. Each of the 1,024 electrodes in a well can detect intracellular action potentials, aside from the traditional extracellular signals. Further, imec’s chip is patterned with microstructures to allow for a structured cell growth mimicking a specific organ.

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Although Hurricane Patricia was one of the most powerful storms ever recorded, that didn’t stop the National Oceanic and Atmospheric Administration (NOAA) from flying a scientific aircraft right through it. Now, the researchers have reported their findings, including the detection of a beam of antimatter being blasted towards the ground, accompanied by flashes of x-rays and gamma rays.

Scientists discovered terrestrial gamma-ray flashes (TGFs) in 1994, when orbiting instruments designed to detect deep space gamma ray bursts noticed signals coming from Earth. These were later linked to storms, and after thousands of subsequent observations have come to be seen as normal parts of lightning strikes.

The mechanisms behind these emissions are still shrouded in mystery, but the basic story goes that, first, the strong electric fields in thunderstorms cause electrons to accelerate to almost the speed of light. As these high-energy electrons scatter off other atoms in the air, they accelerate other electrons, quickly creating an avalanche of what are known as “relativistic” electrons.

Astronomy.com is for anyone who wants to learn more about astronomy events, cosmology, planets, galaxies, asteroids, astrophotography, the Big Bang, black holes, comets, constellations, eclipses, exoplanets, nebulae, meteors, quasars, observing, telescopes, NASA, Hubble, space missions, stargazing, and more.

System-sounds.com converts the orbits of Jupiter moons Io, Europa, Ganymede and Calisto into a mind-bending visual and audio experience.

Researchers at Brown University have discovered a way to stimulate cellular autophagy, which is a natural recycling system built into every cell in the body. This has the potential to combat many age-related neurodegenerative diseases.

What is autophagy?

Autophagy means “eating of self” (from Ancient Greek “auto” = self, “phagein” = to devour). Autophagy is how cells break down broken or dysfunctional organelles and proteins in the cell [1,2]. This essentially means that autophagy can consume organelles, such as mitochondria, peroxisomes, and the endoplasmic reticulum, as part of this process. There is also evidence to support that high levels of autophagy are linked to longevity.

Smart NASA Astrobee robots the size of Jedi training droids will help astronauts on the International Space Station work faster and be more productive.

When history’s pilgrims and pioneers arrived in a new territory, they used the land’s natural resources to build their settlements. Space colonists, on the other hand, will have to bring materials from Earth and assemble them on Mars. Andrew Rush, president and CEO of space-based manufacturing firm Made In Space, believes the process of creating off-world infrastructure will be similar to building IKEA furniture. Only the parts will be made with an advanced 3D printer and put together by an autonomous robot.

“We think the future of in-space operation is one of manufacturing and assembly, just like how you built the table you’re sitting on right now,” Rush says. “That table is a multi-material object, and its pieces were all manufactured in different ways. I don’t think space colonies are going to take a different approach.”

Full of antioxidants and vitamins, tea is pretty good for you, and green tea extracts have even been used as effective carriers for cancer drugs. New research led by Swansea University has found a novel way to wring more health benefits out of the stuff, by making quantum dots from tea leaves and using them to slow the growth of lung cancer cells.

Quantum dots are semiconductor particles so small they exhibit strange electrical and optical properties, such as the ability to fluoresce in different colors, or help with certain chemical reactions. Their glowing properties mean they’re showing up in TVs and solar cells, and in medical applications as biomarkers to help doctors precisely locate tumors. They’re also being used to treat cancer, fight antibiotic-resistant bacteria and convert CO₂ into liquid fuels.

The problem is, manufacturing them can be a costly and complicated process, and the end results can be toxic. So the Swansea team, along with researchers from Bharathiar University and K. S. Rangasamy College of Technology, set about making quantum dots out of humble tea leaves.

Car dealerships in Nordic countries actively discourage consumers from buying electric vehicles, researchers who conducted an undercover investigation said Monday.

Their findings, published in the peer-reviewed Nature Energy, reveal an overlooked barrier to the sale of electric vehicles, which are expected to play a key role in lowering CO₂ emissions and curbing global warming.

Posing as prospective buyers, the researchers made 126 enquiries at 82 dealerships in Denmark, Norway, Sweden, Iceland and Finland.

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