Lifeboat Foundation

An article I wrote:

Study based upon human skeletal muscle aging, mutagenesis, and the role of #satellite cells

“A more comprehensive understanding of the interplay of stem cell–intrinsic and extrinsic factors will set the stage for improving cell therapies capable of restoring tissue homeostasis and enhancing muscle repair in the aged.”

Continue reading “Human Skeletal Muscle Aging and Mutagenesis” »

I ntelligence could be measured with a swab of saliva, or drop of blood, after scientists showed for the first time that a person’s IQ can be predicted just by studying their DNA.

In the largest ever study looking at the genetic basis for intelligence, researchers at the University of Edinburgh and Harvard University discovered hundreds of new genes linked to brain power.

Previous studies have suggested that between 50 per cent and 75 per cent of intelligence is inherited, and the rest comes through upbringing, friendship groups and education. That figure was calculated by studying identical twins who share the same DNA, therefore any differences in IQ between them must be non-genetic.

Continue reading “DNA tests can predict intelligence, scientists show for first time” »

This artist’s impression shows the exoplanet WASP-12b — an alien world as black as fresh asphalt, orbiting a star like our Sun. Scientists were able to measure its albedo: the amount of light the planet reflects. The results showed that the planet is extremely dark at optical wavelengths.

Located 350 million light-years away, two neighbor galaxies are slowly being brought together by gravitational forces.

The Hubble Space Telescope captured the pair’s beautiful cosmic dance in a recent photo of the spiral galaxies, known as Arp 256.

One of the most stunning aspects of the image are the swaths of blue on the outer edges of both galaxies. Those are “stellar nurseries,” collections of gas and dust in the process of becoming new stars. Stellar nurseries are set off by intense gravitational forces, like the massive forces of two galaxies slowly merging.

Continue reading “The Hubble Space Telescope captured two galaxies colliding” »

T he inevitable muscle wasting of old age could be stopped, scientists believe, after discovering why people become frail as they grow older.

Most people become weaker in their later years, as their leg muscles get smaller and less able to bear weight, which often leads to disability and falls.

But until now, nobody has known why the process happens or if it can be reversed.

Continue reading “Inevitable muscle wasting of old age could be stopped, scientists believe” »

John Oliver is a crossover who bridges the art of a comedian with the reporting and perspective of a liberal political pundit. Even detractors acknowledge that Oliver addresses serious issues with unusual wit and humor.

I never thought Oliver could (or would) tackle the topic of cryptocurrency—at least not with value to the viewer. It is too geeky, and too esoteric. (It also cuts into my mission of evangelism and education). smile

He did, and he sparkles! Feel free to jump past the fluff. The Bitcoin tutorial starts at 3:40. Of course, my friend, Shechter, in Long Island New York will bust a gut over what Oliver says at 9:40. It is not only clear and concise, it is accurate and terribly funny!

Whether you are a Bitcoin newbie or a seasoned blockchain coder, this is the video you have been looking for. This one is durable.

Continue reading “John Oliver explains Bitcoin, Blockchain & Crypto (with precision & clarity)!” »

Buzz Aldrin, the second man on the Moon, once said, “Mars is there, waiting to be reached.”

If Elon Musk has his way, he’ll be the one to reach it, even if it’s likely to be a dangerous journey that could result in the loss of human life.

Speaking at the South by South West festival in Austin, Texas, SpaceX and Tesla CEO Musk said he envisions test flights of his Mars spacecraft next year, though he cautioned early trips could end in death.

Continue reading “Elon Musk plans Mars spaceship, warns there’s a ‘good chance’ that early passengers could die” »

Today, I was asked to answer this question at Quora:

“What sets each cryptocurrency apart from the others?”

“Cryptocurrency” is a broad term. It refers to payment coins, of course—such as Bitcoin and Litecoin. But, because most tradeable tokens attain an asset value, the word is often used to refer to smart contract devices, such as Ethereum, a host of other blockchain based tokens, functional Internet-of-Things tokens, and even ICOs (Initial Coin Offerings). Since people treat ICOs and IOT tokens as investment instruments even if they are useless as a payment mechanism, they all fall within the realm of a cryptocurrency.

So, before addressing the question, let’s distinguish between Altcoins and ICOs. I assume the question refers to Altcoins, and not ICOs…

Continue reading “What sets cryptocurrencies apart from each other?” »

Researchers have identified a protein that is different between healthy and cancerous cells, offering a potential target for therapeutic interventions.

Abstract

Sorting nexins anchor trafficking machines to membranes by binding phospholipids. The paradigm of the superfamily is sorting nexin 3 (SNX3), which localizes to early endosomes by recognizing phosphatidylinositol 3-phosphate (PI3P) to initiate retromer-mediated segregation of cargoes to the trans-Golgi network (TGN). Here we report the solution structure of full length human SNX3, and show that PI3P recognition is accompanied by bilayer insertion of a proximal loop in its extended Phox homology (PX) domain. Phosphoinositide (PIP) binding is completely blocked by cancer-linked phosphorylation of a conserved serine beside the stereospecific PI3P pocket. This “PIP-stop” releases endosomal SNX3 to the cytosol, and reveals how protein kinases control membrane assemblies. It constitutes a widespread regulatory element found across the PX superfamily and throughout evolution including of fungi and plants.

Continue reading “A Protein that Shows the Difference Between Cancer and Non-cancer Cells” »