Aging happens in distinct stages marked by synchronized cellular changes across organs, as shown in Rockefeller’s largest-ever mammalian aging atlas. Their findings offer clues for targeting aging processes and reveal key age and sex differences in cellular dynamics.
If you compared photos of a maple tree taken in July and December, the difference would be striking: a vibrant green canopy in summer versus bare, stark branches in winter. What those images wouldn’t reveal is how the transformation unfolded—whether it was gradual or sudden. In reality, deciduous trees usually wait for environmental cues, such as changes in light or temperature, before shedding all their leaves within a brief span of one to two weeks.
When it comes to aging, we may be more like these trees than we realized.
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