Lifeboat Foundation

Unlock the Secret to a Longer, Healthier Life: The Power of Inhibiting IL-11
Discover the groundbreaking science behind aging in this video, Mr. Bill Faloon presents:
• The Role of IL-11 in Aging: Learn how this inflammatory cytokine accelerates aging and contributes to age-related diseases.
• The Benefits of Inhibiting IL-11: Discover how reducing IL-11 levels can lead to increased lifespan, improved health, and a more youthful appearance.
• Natural Ways to Inhibit IL-11: Learn about dietary supplements and lifestyle habits that can help you lower IL-11 levels.
• The Future of Anti-Aging Medicine: Explore the latest research on drugs and therapies targeting IL-11 and how they may revolutionize the way we approach aging.

https://www.nature.com/articles/s41586-024-07701-9
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386112/
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells.

Continue reading “Live Longer, Look Younger: The Groundbreaking Science Of IL-11 Inhibition, 3 Molecules To Reduce It!” »

Researchers at the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) are helping uncover new information about the Y chromosome in horses, which will help owners identify optimal lineages for breeding and help conservationists preserve breed diversity.

“Because of its complex structure, the Y chromosome is much harder to sequence, making our knowledge of it far from complete,” said Dr. Gus Cothran, a professor emeritus in the VMBS’ Department of Veterinary Integrative Biosciences (VIBS). “In fact, scientists used to believe that the Y chromosome lacked genetic variety, which we believed meant that it didn’t contribute much to species diversity.”

However, Cothran’s new research collaboration, led by the University of Veterinary Medicine Vienna, has uncovered that the Y chromosome does have meaningful variation and is important for species diversity.

Before you go 👋 If you want to keep up with the latest news on AI startups and how they’re changing the world, join 1000+ subscribers reading our newsletter for FREE! Link in bio. — - — #samaltman #openai #chatgpt #curecancer #samaltmanquotes #todayinai

Scientists have discovered your cholesterol levels could be significantly linked to your risk of developing dementia. And it’s not just high cholesterol that matters: fluctuating levels over several years could increase your chances of the disease by 60 per cent, suggests a new study of 10,000 people.

The research also suggests that, even if you don’t develop dementia, a large cholesterol variability – swinging from high to low levels – is linked to an increased risk of general cognitive decline by 23 per cent.

Summary: Scientists have reprogrammed mouse cells into pluripotent stem cells using a gene from choanoflagellates, single-celled organisms related to animals. This breakthrough demonstrates that key genes driving stem cell formation existed in unicellular ancestors nearly a billion years ago.

The resulting stem cells were used to create a chimeric mouse, showcasing how ancient genetic tools can integrate with modern mammalian biology. This discovery redefines the evolutionary origins of stem cells and may inform regenerative medicine advancements.

Minuscule particles of plastic are not only bad for the environment. A study led from Umeå University, Sweden, has shown that the so-called nanoplastics which enter the body also can impair the effect of antibiotic treatment. The results also indicate that the nanoplastics may lead to the development of antibiotic resistance. Even the indoor air in our homes contains high levels of nanoplastics from, among other things, nylon, which is particularly problematic.

“The results are alarming considering how common nanoplastics are and because effective antibiotics for many can be the difference between life and death,” says Lukas Kenner, professor at the Department of Molecular Biology at Umeå University and one of the researchers who led the study.

Nanoplastics are plastic particles that are smaller than a thousandth of a millimetre. Due to their smallness, they can float freely in the air and have the ability to enter the body.

Despite being a mature technology in existence for over several decades, silicon photonic modulators face scrutiny from industry and academic experts. In a recent editorial interview, experts emphasize the need to explore alternatives beyond the traditional platforms. The discussion centers on innovative modulator materials and configurations that could cater to emerging applications in data centers, artificial intelligence, quantum information processing, and LIDAR. Experts also outline the challenges that lie ahead in this field.

Optical and photonic modulators are technologically advanced devices that enable the manipulation of light properties—such as power and phase—based on input signals. Over the decades, scientists have researched and developed silicon photonic modulators with wide-ranging applications, including optical data communication, sensing, biomedical technologies, automotive systems, astronomy, aerospace, and artificial intelligence (AI).

However, these modulators face bandwidth limitations and operational robustness issues stemming from the fundamental properties of silicon and other practical constraints, as highlighted by a panel of leading industry and academic experts in a recent editorial interview.

Can weight loss leave a lasting imprint on our fat cells?

Losing weight is often touted as a cornerstone of better health, particularly for people dealing with obesity and its associated health risks.

Anyone who has ever tried to get rid of a few extra kilos knows the frustration: the weight drops initially, only to be back within a matter of weeks—the yo-yo effect has struck. Researchers at ETH Zurich have now been able to show that this is all down to epigenetics.

Continue reading “Fat cells have epigenetics-based memory: Researchers discover mechanism behind weight loss yo-yo effect” »

Using data and samples from volunteers, including Kaiser Permanente Washington members participating in the Adult Changes in Thought Study (ACT Study), the researchers used advanced genomic technologies and machine learning models to create a timeline of the cellular and molecular changes caused by…

Mapping the disease at the cellular level identifies possible new treatment targets.