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Archive for the ‘chemistry’ category: Page 13

Sep 21, 2024

The Hidden Biochemistry of Cold Temperatures: Chilling RNA Discovery Reshapes the Rules of Life

Posted by in categories: biotech/medical, chemistry, evolution, genetics, nanotechnology

Ribonucleic acid (RNA) is a vital biological molecule that plays a significant role in the genetics of organisms and is essential to the origin and evolution of life. Structurally similar to DNA, RNA carries out various biological functions, largely determined by its spatial conformation, i.e. the way the molecule folds in on itself.

Now, a paper published in the journal Proceedings of the National Academy of Sciences (PNAS) describes for the first time how the process of RNA folding at low temperatures may open up a novel perspective on primordial biochemistry and the evolution of life on the planet.

The study is led by Professor Fèlix Ritort, from the Faculty of Physics and the Institute of Nanoscience and Nanotechnology (IN2UB) of the University of Barcelona, and is also signed by UB experts Paolo Rissone, Aurélien Severino, and Isabel Pastor.

Sep 18, 2024

A refresh-in-sensing reusable biosensor

Posted by in categories: biotech/medical, chemistry

An electrochemical biosensor capable of detecting low levels of cancer biomarkers is reusable over 200 regeneration cycles without compromising device sensitivity and accuracy.

Sep 18, 2024

New technology produces ultrashort ion pulses

Posted by in categories: chemistry, materials

TU Wien (Vienna) has succeeded in generating laser-synchronized ion pulses with a duration of well under 500 picoseconds, which can be used to observe chemical processes on material surfaces. The work has been published in Physical Review Research.

Sep 17, 2024

Scientists just figured out how many chemicals enter our bodies from food packaging

Posted by in categories: chemistry, food

More than 3,000 chemicals from food packaging have infiltrated our bodies, a new study has found.

Sep 17, 2024

Is life a complex computational process?

Posted by in categories: biotech/medical, chemistry, computing, genetics

However, more recent research suggests there are likely countless other possibilities for how life might emerge through potential chemical combinations. As the British chemist Lee Cronin, the American theoretical physicist Sara Walker and others have recently argued, seeking near-miraculous coincidences of chemistry can narrow our ability to find other processes meaningful to life. In fact, most chemical reactions, whether they take place on Earth or elsewhere in the Universe, are not connected to life. Chemistry alone is not enough to identify whether something is alive, which is why researchers seeking the origin of life must use other methods to make accurate judgments.

Today, ‘adaptive function’ is the primary criterion for identifying the right kinds of biotic chemistry that give rise to life, as the theoretical biologist Michael Lachmann (our colleague at the Santa Fe Institute) likes to point out. In the sciences, adaptive function refers to an organism’s capacity to biologically change, evolve or, put another way, solve problems. ‘Problem-solving’ may seem more closely related to the domains of society, culture and technology than to the domain of biology. We might think of the problem of migrating to new islands, which was solved when humans learned to navigate ocean currents, or the problem of plotting trajectories, which our species solved by learning to calculate angles, or even the problem of shelter, which we solved by building homes. But genetic evolution also involves problem-solving. Insect wings solve the ‘problem’ of flight. Optical lenses that focus light solve the ‘problem’ of vision. And the kidneys solve the ‘problem’ of filtering blood. This kind of biological problem-solving – an outcome of natural selection and genetic drift – is conventionally called ‘adaptation’. Though it is crucial to the evolution of life, new research suggests it may also be crucial to the origins of life.

This problem-solving perspective is radically altering our knowledge of the Universe. Life is starting to look a lot less like an outcome of chemistry and physics, and more like a computational process.

Sep 17, 2024

Using sunlight to turn two greenhouse gases into valuable chemicals

Posted by in categories: chemistry, climatology, sustainability

McGill University researchers have harnessed the power of sunlight to transform two of the most harmful greenhouse gases into valuable chemicals. The discovery could help combat climate change and provide a more sustainable way to produce certain industrial products.

“Imagine a world where the exhaust from your car or emissions from a factory could be transformed, with the help of sunlight, into clean fuel for vehicles, the building blocks for everyday plastics, and energy stored in batteries,” said co-first author Hui Su, a Postdoctoral Fellow in McGill’s Department of Chemistry. “That’s precisely the kind of transformation this new chemical process enables.”

The research team’s new light-driven chemical process converts methane and carbon dioxide into green methanol and carbon monoxide in one reaction. Both products are highly valued in the chemical and energy sectors, the researchers said.

Sep 16, 2024

Inspired by squids and octopi, a new screen stores and displays encrypted images without electronics

Posted by in categories: chemistry, computing, encryption, engineering

A flexible screen inspired in part by squid can store and display encrypted images like a computer—using magnetic fields rather than electronics. The research is reported in Advanced Materials by University of Michigan engineers.

“It’s one of the first times where mechanical materials use magnetic fields for system-level encryption, information processing and computing. And unlike some earlier mechanical computers, this device can wrap around your wrist,” said Joerg Lahann, the Wolfgang Pauli Collegiate Professor of Chemical Engineering and co-corresponding author of the study.

Continue reading “Inspired by squids and octopi, a new screen stores and displays encrypted images without electronics” »

Sep 16, 2024

Dr. Francis Collins — Former Director, U.S. National Institutes Of Health (NIH) — The Road To Wisdom

Posted by in categories: biotech/medical, chemistry, genetics, life extension

The Road To Wisdom — Dr. Francis Collins, MD, PhD — Former Director, National Institutes of Health (NIH); Distinguished Investigator, Center for Precision Health Research, National Human Genome Research Institute.


Dr. Francis S. Collins, M.D., Ph.D., (https://www.francisscollins.com/) is the former Director of the U.S. National Institutes of Health (NIH), where as the longest serving director of NIH (spanning 12 years and three presidencies) he oversaw the work of the largest supporter of biomedical research in the world, from basic to clinical research.

Continue reading “Dr. Francis Collins — Former Director, U.S. National Institutes Of Health (NIH) — The Road To Wisdom” »

Sep 15, 2024

CO2 turned into fuel with Japan’s electrochemical cell breakthrough

Posted by in categories: chemistry, sustainability

Researchers develop a new electrochemical cell that efficiently converts captured carbon dioxide into formate, a clean fuel source.

Sep 15, 2024

Microtubule-Stabilizer Epothilone B Delays Anesthetic-Induced Unconsciousness in Rats

Posted by in categories: biotech/medical, chemistry, neuroscience, quantum physics

Volatile anesthetics reversibly abolish consciousness or motility in animals, plants, and single-celled organisms (Kelz and Mashour, 2019; Yokawa et al., 2019). For humans, they are a medical miracle that we have been benefiting from for over 150 years, but the precise molecular mechanisms by which these molecules reversibly abolish consciousness remain elusive (Eger et al., 2008; Hemmings et al., 2019; Kelz and Mashour, 2019; Mashour, 2024). The functionally relevant molecular targets for causing unconsciousness are believed to be one or a combination of neural ion channels, receptors, mitochondria, synaptic proteins, and cytoskeletal proteins.

The Meyer–Overton correlation refers to the venerable finding that the anesthetic potency of chemically diverse anesthetic molecules is directly correlated with their solubility in lipids akin to olive oil (S. R. Hameroff, 2018; Kelz and Mashour, 2019). The possibility that general anesthesia might be explained by unitary action of all (or most) anesthetics on one target protein is supported by the Meyer–Overton correlation and the additivity of potencies of different anesthetics (Eger et al., 2008). Together these results suggest that anesthetics may act on a unitary site, via relatively nonspecific physical interactions (such as London/van der Waals forces between induced dipoles).

Cytoskeletal microtubules (MTs) have been considered as a candidate target of anesthetic action for over 50 years (Allison and Nunn, 1968; S. Hameroff, 1998). Other membrane receptor and ion channel proteins were ruled out as possible unitary targets by exhaustive studies culminating in Eger et al. (2008). However, MTs (composed of tubulin subunits) were not ruled out and remain a candidate for a unitary site of anesthetic action. MTs are the major components of the cytoskeleton in all cells, and they also play an essential role in cell reproduction—and aberrant cell reproduction in cancer—but in neurons, they have additional specialized roles in intracellular transport and neural plasticity (Kapitein and Hoogenraad, 2015). MTs have also been proposed to process information, encode memory, and mediate consciousness (S. R. Hameroff et al., 1982; S. Hameroff and Penrose, 1996; S. Hameroff, 2022). While classical models predict no direct role of MTs in neuronal membrane and synaptic signaling, Singh et al. (2021a) showed that MT activities do regulate axonal firing, for example, overriding membrane potentials. The orchestrated objective reduction (Orch OR) theory proposes that anesthesia directly blocks quantum effects in MTs necessary for consciousness (S. Hameroff and Penrose, 2014). Consistent with this hypothesis, volatile anesthetics do bind to cytoskeletal MTs (Pan et al., 2008) and dampen their quantum optical effects (Kalra et al., 2023), potentially contributing to causing unconsciousness.

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