Lifeboat Foundation

For the first time, an artificial molecular motor has been created that can ‘talk’ to living cells – by gently pulling their surface with enough physical force to elicit a biochemical response. The approach could help scientists decode the language that cells use to communicate with each other in tissues.

‘There is a mechanical language in the form of physical forces applied by the cells themselves, and we want to understand what information is communicated and what the consequences are,’ explains Aránzazu del Campo, who led the study at the Leibniz Institute for New Materials, Germany. ‘Ultimately, we want to be able to provide signals to cells and guide their function when they are not able to do that by themselves in disease cases.’

Usually, studying how cells communicate by sensing mechanical stimuli and producing biochemical responses requires prodding them with pipettes or the tip of an atomic force microscope. However, this doesn’t work at the more complex tissue level.

“I realized that in the middle-dose group, which is the one that mattered for the no-effects level, they had conveniently left out one of the two baseline measurement days,” said Sheppard. “The outrageous thing was that the group they declared as NOEL was only that because they left out data from their analysis.” In a peer-reviewed paper published in October 2020, Sheppard and her colleagues concluded that “the omission of valid data without justification was a form of data falsification.”

In any case, bifenthrin was not the only pesticide that dodged testing to see if it presented dangers. The EPA’s pesticide office granted 972 industry requests to waive toxicity tests between December 2011 and May 2018, 89 percent of all requests made. Among the tests on pesticides that were never performed were 90 percent of tests looking for developmental neurotoxicity, 92 percent of chronic cancer studies, and 97 percent of studies looking at how pesticides harm the immune system.

By law, the companies that submit their products for review pay for these tests, and in a presentation about the waivers last year, Anna Lowit, a senior science adviser in the office, emphasized the savings to these companies: more than $300 million. Lowit also noted that animal lives were saved — a goal that the Trump administration and the chemical industry prioritized within the agency. The EPA developed the guidelines for waiving the tests along with BASF, Corteva, and Syngenta, pesticide manufacturers that all stand to benefit significantly from having their products bypass toxicity testing.

Continue reading “How Pesticide Companies Corrupted the EPA and Poisoned America” »

Researchers have created an unusual new alloy made up of not two, but five different metals, and put it to work as a catalyst. The new material is two-dimensional, and was able to convert carbon dioxide into carbon monoxide effectively, potentially helping to turn the greenhouse gas into fuels.

The new alloy belongs to a class of materials called transition metal dichalcogenides (TMDCs), which are, as the name suggests, made up of combinations of transition metals and chalcogens. Extremely thin films of TMDCs have recently shown promise in a range of electronic and optical devices, but researchers on the new study wondered if they could also be used as catalysts for chemical reactions.

The thinking goes that because reactions occur on the surface of a catalyst, materials with high surface areas will be more effective catalysts. And as sheets only a few atoms thick, TMDCs are almost nothing but surface area.

It’s a problem that few of us will likely ever face: once you’ve built your first homemade integrated circuit, what do you do next? If you’re [Sam Zeloof], the answer is clear: build better integrated circuits.

At least that’s [Sam]’s plan, which his new reactive-ion etching setup aims to make possible. While his Z1 dual differential amplifier chip was a huge success, the photolithography process he used to create the chip had its limitations. The chemical etching process he used is a bit fussy, and prone to undercutting of the mask if the etchant seeps underneath it. As its name implies, RIE uses a plasma of highly reactive ions to do the etching instead, resulting in finer details and opening the door to using more advanced materials.

Continue reading “Garage Semiconductor Fab Gets Reactive-Ion Etching Upgrade” »

University of Colorado Boulder researchers have discovered that minuscule, self-propelled particles called “nanoswimmers” can escape from mazes as much as 20 times faster than other passive particles, paving the way for their use in everything from industrial clean-ups to medication delivery.

The findings, published this week in the Proceedings of the National Academy of Sciences, describe how these tiny synthetic nanorobots are incredibly effective at escaping cavities within maze-like environments. These nanoswimmers could one day be used to remediate contaminated soil, improve water filtration or even deliver drugs to targeted areas of the body, like within dense tissues.

“This is the discovery of an entirely new phenomenon that points to a broad potential range of applications,” said Daniel Schwartz, senior author of the paper and Glenn L. Murphy Endowed Professor of chemical and biological engineering.

The US power grid needs all of support it can get. Sad that some would stand in the way of progress.

There is no love lost between the notorious Koch brothers and the nation’s railroad industry, and the relationship is about to get a lot unlovelier. A massive new, first-of-its-kind renewable energy transmission line is taking shape in the Midwest, which will cut into the Koch family’s fossil energy business. It has a good chance of succeeding where others have stalled, because it will bury the cables under existing rights-of-way using railroad rights-of-way and avoid stirring up the kind of opposition faced by conventional above-ground lines.

The Koch brothers and their family-owned company, Koch Industries, have earned a reputation for attempting to throttle the nation’s renewable energy sector. That makes sense, considering that the diversified, multinational firm owns thousands of miles of oil, gas, and chemical pipelines criss-crossing the US (and sometimes breaking down) in addition to other major operations that depend on rail and highway infrastructure.

Continue reading “Railroads To Pour Cold Renewable Energy Water On Koch Industries” »

Material scientists have developed a fast method for producing epsilon iron oxide and demonstrated its promise for next-generation communications devices. Its outstanding magnetic properties make it one of the most coveted materials, such as for the upcoming 6G generation of communication devices and for durable magnetic recording. The work was published in the Journal of Materials Chemistry C, a journal of the Royal Society of Chemistry.

Iron oxide (III) is one of the most widespread oxides on Earth. It is mostly found as the mineral hematite (or alpha iron oxide, α-Fe₂O₃). Another stable and common modification is maghemite (or gamma modification, γ-Fe₂O₃). The former is widely used in industry as a red pigment, and the latter as a magnetic recording medium. The two modifications differ not only in crystalline structure (alpha-iron oxide has hexagonal syngony and gamma-iron oxide has cubic syngony) but also in magnetic properties.

In addition to these forms of iron oxide (III), there are more exotic modifications such as epsilon-, beta-, zeta-, and even glassy. The most attractive phase is epsilon iron oxide, ε-Fe₂O₃. This modification has an extremely high coercive force (the ability of the material to resist an external magnetic field). The strength reaches 20 kOe at room temperature, which is comparable to the parameters of magnets based on expensive rare-earth elements. Furthermore, the material absorbs electromagnetic radiation in the sub-terahertz frequency range (100−300 GHz) through the effect of natural ferromagnetic resonance. The frequency of such resonance is one of the criteria for the use of materials in wireless communications devices—the 4G standard uses megahertz and 5G uses tens of gigahertz. There are plans to use the sub-terahertz range as a working range in the sixth generation (6G) wireless technology, which is being prepared for active introduction in our lives from the early 2030s.

The new system streamlines the process of fermenting plant sugar to fuel by helping yeast survive industrial toxins.

More corn is grown in the United States than any other crop, but we only use a small part of the plant for food and fuel production; once people have harvested the kernels, the inedible leaves, stalks and cobs are left over. If this plant matter, called corn stover, could be efficiently fermented into ethanol the way corn kernels are, stover could be a large-scale, renewable source of fuel.

“Stover is produced in huge amounts, on the scale of petroleum,” said Whitehead Institute Member and Massachusetts Institute of Technology (MIT) biology professor Gerald Fink. “But there are enormous technical challenges to using them cheaply to create biofuels and other important chemicals.”

In fall of 2019, we demonstrated that the Sycamore quantum processor could outperform the most powerful classical computers when applied to a tailor-made problem. The next challenge is to extend this result to solve practical problems in materials science, chemistry and physics. But going beyond the capabilities of classical computers for these problems is challenging and will require new insights to achieve state-of-the-art accuracy. Generally, the difficulty in performing quantum simulations of such physical problems is rooted in the wave nature of quantum particles, where deviations in the initial setup, interference from the environment, or small errors in the calculations can lead to large deviations in the computational result.

In two upcoming publications, we outline a blueprint for achieving record levels of precision for the task of simulating quantum materials. In the first work, we consider one-dimensional systems, like thin wires, and demonstrate how to accurately compute electronic properties, such as current and conductance. In the second work, we show how to map the Fermi-Hubbard model, which describes interacting electrons, to a quantum processor in order to simulate important physical properties. These works take a significant step towards realizing our long-term goal of simulating more complex systems with practical applications, like batteries and pharmaceuticals.