Lifeboat Foundation

Batteries with high energy densities could enable the creation of a wider range of electric vehicles, including flying vehicles that can transport humans in urban environments. Past studies predict that to support the operation of vehicles capable of take-off and landing, batteries require energy densities of approximately 400 Wh kg^-1 at the cell level, which is approximately 30% higher than the energy density of most existing lithium-ion (Li-ion) cells.

In addition to powering flying vehicles, high-energy cells (i.e., single units within a battery that convert chemical into electrical energy) could increase the distance that electric cars can travel before they need to be charged again. They may also reduce overall fabrication costs for electric vehicles, as similar results could be achieved using fewer but better-performing cells.

Anode-free lithium metal cells are particularly promising for creating batteries with higher energy densities. While they use the same cathode as Li-ion cells, these cells store energy via an electroplated lithium metal instead of a graphite host, and they can have energy densities that are 60% greater than those of Li-ion cells.

For years, researchers have aimed to learn more about a group of metal oxides that show promise as key materials for the next generation of lithium-ion batteries because of their mysterious ability to store significantly more energy than should be possible. An international research team, co-led by The University of Texas at Austin, has cracked the code of this scientific anomaly, knocking down a barrier to building ultra-fast battery energy storage systems.

The team found that these metal oxides possess unique ways to store energy beyond classic electrochemical storage mechanisms. The research, published in Nature Materials, found several types of metal compounds with up to three times the energy storage capability compared with materials common in today’s commercially available lithium-ion batteries.

By decoding this mystery, the researchers are helping unlock batteries with greater energy capacity. That could mean smaller, more powerful batteries able to rapidly deliver charges for everything from smartphones to electric vehicles.

A downsized version of the company’s Sycamore chip performed a record-breaking simulation of a chemical reaction.

The moon is turning ever so slightly red, and it’s likely Earth’s fault. Our planet’s atmosphere may be causing the moon to rust, new research finds.

Rust, also known as an iron oxide, is a reddish compound that forms when iron is exposed to water and oxygen. Rust is the result of a common chemical reaction for nails, gates, the Grand Canyon’s red rocks — and even Mars. The Red Planet is nicknamed after its reddish hue that comes from the rust it acquired long ago when iron on its surface combined with oxygen and water, according to a statement from NASA’s Jet Propulsion Laboratory (JPL) in Pasadena, California.

Cellular Aquaculture — Feed The World and Save the Oceans — Lou Cooperhouse, President & CEO, of BlueNalu, joins me on ideaXme (https://radioideaxme.com/) to discuss his company’s technologies to provide the world with healthy and safe cell-based seafood products, and support the sustainability and diversity of our oceans — #Ideaxme #StemCells #Aquaculture #Oceans #Fish #Sushi #Poke #Ceviche #SustainableDevelopment #Agriculture #Health #Wellness #RegenerativeMedicine #Biotech #Longevity #Aging #IraPastor #Bioquark #Regenerage ideaXme BlueNalu Rutgers University Rich Products Sumitomo Chemical: Group Companies of the Americas KBW Investments.

Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Lou Cooperhouse, President and CEO of BlueNalu.

Continue reading “Feeding the World with Cellular Aquaculture: Food Security and Sustainability” »

Cardiovascular-related disorders are a significant worldwide health problem. Cardiovascular disease (CVD) is the leading cause of death in developed countries, making up a third of the mortality rate in the US¹. Congenital heart defects (CHD) affect ∼1% of all live births², making it the most common birth defect in humans. Current technologies provide some insight into how these disorders originate but are limited in their ability to provide a complete overview of disease pathogenesis and progression due to their lack of physiological complexity. There is a pressing need to develop more faithful organ-like platforms recapitulating complex in vivo phenotypes to study human development and disease in vitro. Here, we report the most faithful in vitro organoid model of human cardiovascular development to date using human pluripotent stem cells (hPSCs). Our protocol is highly efficient, scalable, shows high reproducibility and is compatible with high-throughput approaches. Furthermore, our hPSC-based heart organoids (hHOs) showed very high similarity to human fetal hearts, both morphologically and in cell-type complexity. hHOs were differentiated using a two-step manipulation of Wnt signaling using chemical inhibitors and growth factors in completely defined media and culture conditions. Organoids were successfully derived from multiple independent hPSCs lines with very similar efficiency. hHOs started beating at ∼6 days, were mostly spherical and grew up to ∼1 mm in diameter by day 15 of differentiation. hHOs developed sophisticated, interconnected internal chambers and confocal analysis for cardiac markers revealed the presence of all major cardiac lineages, including cardiomyocytes (TNNT2⁺), epicardial cells (WT1⁺, TJP⁺), cardiac fibroblasts (THY1⁺, VIM⁺), endothelial cells (PECAM1⁺), and endocardial cells (NFATC1⁺). Morphologically, hHOs developed well-defined epicardial and adjacent myocardial regions and presented a distinct vascular plexus as well as endocardial-lined microchambers. RNA-seq time-course analysis of hHOs, monolayer differentiated iPSCs and fetal human hearts revealed that hHOs recapitulate human fetal heart tissue development better than previously described differentiation protocols^3,4. hHOs allow higher-order interaction of distinct heart tissues for the first time and display biologically relevant physical and topographical 3D cues that closely resemble the human fetal heart. Our model constitutes a powerful novel tool for discovery and translational studies in human cardiac development and disease.

The authors have declared no competing interest.

A new exciting life detection toolset for exploration of an alien planet or moon.

Life detection on Mars and the icy moons of the outer Solar System looks more and more feasible.

For the past 70 years, most of humanity’s rockets have been chemical rockets- with either liquid or solid fuel. However, it may be possible for future rockets to use different fuel sources.

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