Lifeboat Foundation

Not science, apparentlyLast month, a Ph.D. student at the Hebrew University of Jerusalem breed a new strain of ‘supercharged’ lettuce that expanded its vitamin C and beta carotene content by 800 percent and 70 percent respectively.

Research Interests.

Genomic/metabolomic/proteomic approaches for identification of novel (regulatory and biosynthetic) aroma genes.

Continue reading “What is stopping gene-edited food from saving our planet?” »

New Israeli startup aims to get product to market within two years; technology could also be used to identify early markers of cancer.

An Israeli startup is developing a non-invasive early detection method using artificial intelligence (AI) to identify genetic disorders in human embryos.

Via a simple blood test taken from the pregnant mother during the first trimester, IdentifAI Genetics can read the embryo’s entire DNA and provide in-depth analysis to detect genetic disorders.

Multiple changes in brain cells during the first month of embryonic development may contribute to schizophrenia later in life, according to a new study by Weill Cornell Medicine investigators.

The researchers, whose study was published in Molecular Psychiatry, used stem cells collected from patients with schizophrenia and people without the disease to grow 3-dimensional “mini-brains” or organoids in the laboratory. By comparing the development of both sets of organoids, they discovered that a reduced expression of two genes in the cells stymies early development and causes a shortage of brain cells in organoids grown from patient stem cells.

“This discovery fills an important gap in scientists’ understanding of schizophrenia,” said senior author Dr. Dilek Colak, assistant professor of neuroscience at the Feil Family Brain and Mind Institute and the Center for Neurogenetics at Weill Cornell Medicine. Symptoms of schizophrenia typically develop in adulthood, but postmortem studies of the brains of people with the disease found enlarged cavities called ventricles and differences in the cortical layers that likely occurred early in life.

A cloud-based repository that creates a digital fingerprint of engineered microorganisms has been successfully trialed.

An international team led by Newcastle University has launched CellRepo, a species and strain database that uses cell barcodes to monitor and track engineered organisms. Reported in a new study in the journal Nature Communications, the database keeps track and organizes the digital data produced during cell engineering. It also molecularly links that data to the associated living samples.

Available globally, this resource supports international collaboration and has significant safety advantages, such as limiting the impact of deliberately or accidentally released genetically modified microorganisms by enabling faster tracing of organisms lab of origin and design details.

Coffee, wine, and wheat varieties are among the foods we could lose forever.

The grocery store is thin on genetic diversity. Bringing back endangered foods can help.

For children suffering from rare diseases, it usually takes years to receive a diagnosis. This “diagnostic odyssey” is filled with multiple referrals and a barrage of tests, seeking to uncover the root cause behind mysterious and debilitating symptoms.

A new speed record in DNA sequencing may soon help families more quickly find answers to difficult and life-altering questions.

Continue reading “Rapid DNA Sequencing Tech Breaks the Speed Record for Reading Whole Genomes” »

Available treatments work equally well against the variant.

A newfound variant of HIV, the virus that causes AIDS, has been uncovered in the Netherlands and appears to cause faster disease progression compared with other versions of the virus.

The human immunodeficiency virus (HIV) infects and destroys immune cells called CD4 cells in the body, causing the number of these cells to plummet. If left untreated, the infection then progresses to AIDS. In people infected with the newfound HIV variant, called the VB variant, the CD4 counts fall at about twice the rate as those of people infected with closely related HIV strains, meaning those of the same genetic subtype (B).

Concetta Antico is the world’s most famous tetrachromat, meaning she has four types of color receptors (cone cells) in her eyes. Most of us have three types. As a result of this mutation, Antico can see around 100 million colors, 100 times more than other people. Antico is an artist and she says that her psychedelic color paintings depict what she perceives. I wonder though what her paintings look like through her eyes. From The Guardian:

According to Dr Kimberly Jameson, a University of California scientist who has studied Antico, just having the gene – which around 15% of women have – is not alone sufficient to be a tetrachromat, but it’s a necessary condition. “In Concetta’s case … one thing we believe is that because she’s been painting sort of continuously since the age of seven years old, she has really enlisted this extra potential and used it. This is how genetics works: it gives you the potential to do things and if the environment demands that you do that thing, then the genes kick in.”[…]

Continue reading “Meet the artist whose genetic mutation means she can see 100 times more colors than you” »

Long-lasting leukemia remission prompts doctors to call CAR-T cell therapy a ‘cure’ for some.