Lifeboat Foundation

Imagine swabbing your nostrils, putting the swab in a device, and getting a read-out on your phone in 15 to 30 minutes that tells you if you are infected with the COVID-19 virus. This has been the vision for a team of scientists at Gladstone Institutes, University of California, Berkeley (UC Berkeley), and University of California, San Francisco (UCSF). And now, they report a scientific breakthrough that brings them closer to making this vision a reality.

One of the major hurdles to combating the COVID-19 pandemic and fully reopening communities across the country is the availability of mass rapid testing. Knowing who is infected would provide valuable insights about the potential spread and threat of the virus for policymakers and citizens alike.

Yet, people must often wait several days for their results, or even longer when there is a backlog in processing lab tests. And, the situation is worsened by the fact that most infected people have mild or no symptoms, yet still carry and spread the virus.

According to U.S. officials, China is experimenting on humans using the gene-editing technique called CRISPR.

Exploring the frontiers of neuromodulation, neurostimulation, and neural interfaces.

Neuromodulation is defined as “the alteration of nerve activity through targeted delivery of a stimulus, such as electrical stimulation or chemical agents, to specific neurological sites in the body”. It is carried out to normalize – or modulate – nervous tissue function.

Continue reading “Dr. Amilcar dos Santos MD — Exploring Far Frontiers of Neural, Spinal, and Brain-Computer Interfaces” »

Scientists have recovered DNA from a well-preserved horned lark found in Siberian permafrost. The results can contribute to explaining the evolution of sub species, as well as how the mammoth steppe transformed into tundra, forest and steppe biomes at the end of the last Ice Age.

In 2018, a well-preserved frozen bird was found in the ground in the Belaya Gora area of north-eastern Siberia. Researchers at the Centre for Palaeogenetics, a new research center at Stockholm University and the Swedish Museum of Natural History, haves studied the bird and the results are now published in the scientific journal Communications Biology. The analyses reveals that the bird is a 46,000-year-old female horned lark.

“Not only can we identify the bird as a horned lark. The genetic analysis also suggests that the bird belonged to a population that was a joint ancestor of two sub species of horned lark living today, one in Siberia, and one in the steppe in Mongolia. This helps us understand how the diversity of sub species evolves,” says Nicolas Dussex, researcher at the Department of Zoology at Stockholm University.

Cellular reprogramming can reverse the aging that leads to a decline in the activities and functions of mesenchymal stem/stromal cells (MSCs). This is something that scientists have known for a while. But what they had not figured out is which molecular mechanisms are responsible for this reversal. A study released today in STEM CELLS appears to have solved this mystery. It not only enhances the knowledge of MSC aging and associated diseases, but also provides insight into developing pharmacological strategies to reduce or reverse the aging process.

The research team, made up of scientists at the University of Wisconsin-Madison, relied on cellular reprogramming — a commonly used approach to reverse cell aging — to establish a genetically identical young and old cell model for this study. “While agreeing with previous findings in MSC rejuvenation by cellular reprogramming, our study goes further to provide insight into how reprogrammed MSCs are regulated molecularly to ameliorate the cellular hallmarks of aging,” explained lead investigator, Wan-Ju Li, Ph.D., a faculty member in the Department of Orthopedics and Rehabilitation and the Department of Biomedical Engineering.

https://www.youtube.com/watch?v=12YKjOnxrxI

Original Video ► https://www.youtube.com/watch?v=W_23474cHLg&ab_channel=RT

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Continue reading “David Sinclair — Aging Can Be Cured” »

Methylation definition at 5:05, 27:20 a lil about reprogramming, 32:00 q&a, 47:44 Aubrey chimes in, 57:00 Keith Comito(and other throughout)

Zoom transcription: https://otter.ai/u/AIIhn4i_p4DIXHAJx0ZaG0HUnAU

Continue reading “Underlying Features of Epigenetic Aging Clocks | Morgan Levine, Yale University” »

AI, Genetics, and Health-Tech / Wearables — 21st Century Technologies For Healthy Companion Animals.

Ira Pastor ideaXme life sciences ambassador interviews Dr. Angela Hughes, the Global Scientific Advocacy Relations Senior Manager and Veterinary Geneticist at Mars Petcare.

Continue reading “Mars Personalised Petcare: High Tech, Genetics and Wearables” »

These findings […] strongly suggest that high levels of iron in the blood reduces our healthy years of life, and keeping these levels in check could prevent age-related damage.

Genes linked to ageing that could help explain why some people age at different rates to others have been identified by scientists.

The international study using genetic data from more than a million people suggests that maintaining healthy levels of iron in the blood could be a key to ageing better and living longer.

Continue reading “Blood iron levels could be key to slowing ageing, gene study shows” »