Lifeboat Foundation

A new computational method can identify how cause-and-effect relationships ebb and flow over time in dynamic real-life systems such as the brain.

Male and female mice use different brain circuits to process threats, revealing sex-specific neural pathways despite similar behaviors. These findings suggest the need for sex-inclusive neuroscience research to improve understanding and treatments.

Satellite Data Reveals How Environment Shapes Kids’ Brain Health https://neurosciencenews.com/environment-brain-development-28026/

Adverse childhood experiences can lead to adult symptoms of anxiety and depression, mediated by life history strategies, according to a study published in Biodemography & Social Biology.

Existing research underscores the psychological impact of early-life adversity, with theories across cognitive, behavioral, and evolutionary psychology exploring these long-term effects. The life history theory, specifically, offers insight by framing adverse childhood experiences (ACEs) in terms of fast or slow life strategies, each with distinct reproductive and developmental adaptations suited to one’s environment.

Continue reading “Study examines how early experiences shape our mental health trajectory” »

YouTube videos on autism primarily provide educational content with balanced perspectives, reducing stigmatization, though viewer comments often remain negative. This highlights YouTube’s dual role in improving understanding while revealing persistent public misconceptions.

Substance use disorders are a group of conditions involving the recurrent use of substances, like drugs or alcohol, despite harmful consequences to physical, mental, or social health. These disorders are characterized by an inability to control usage, intense cravings, and continued use despite negative impacts on relationships, work, or health.

While it is well-known that substance use disorders have negative consequences for the individual, research has recently begun to focus on the effects of these disorders on others, known as the “harm to others” framework. A key area of these studies is the impact on children growing up with parents affected by substance use disorders. These children have been found to have lower academic achievement than their peers whose parents do not have such disorders, as well as an increased risk of various mental health and developmental issues.

Study author Hélio Manhica and his colleagues aimed to explore the mental health risks for children of parents with substance use disorders in greater detail. They also sought to determine whether these risks differ between males and females and if certain periods in childhood or adolescence are particularly critical in relation to exposure to parental substance use disorder (i.e., periods that influence the overall risk of developing psychiatric disorders).

A groundbreaking study using PET scans has revealed that autistic individuals have fewer brain synapses, directly correlating with more pronounced autism traits like social and communication challenges.

This discovery, illustrating clear links between brain structure and behavioral expressions, could revolutionize diagnostic approaches and enhance support mechanisms, potentially leading to more targeted interventions and improved quality of life for those on the autism spectrum.

Synaptic Research in Autism.

Summary: Researchers found that exercise promotes neuron growth through both biochemical signals (myokines) and physical stretching. Muscle cells, when contracted, release myokines that boost neuron growth and maturity. Furthermore, neurons that were “exercised” through mechanical movement grew just as much as those exposed to myokines.

These findings reveal the dual role of exercise in stimulating nerves, offering hope for developing therapies targeting nerve repair and neurodegenerative diseases. This research opens new avenues in treating nerve damage through “exercise as medicine.”

Researchers found that neural crest stem cells are uniquely capable of reprogramming, challenging current reprogramming theories and opening possibilities for stem cell-based treatments.

A research team from the University of Toronto has identified that neural crest stem cells, a group of cells found in the skin and other parts of the body, are the origin of reprogrammed neurons previously found by other scientists.

Their findings refute the popular theory in cellular reprogramming that any developed cell can be induced to switch its identity to a completely unrelated cell type through the infusion of transcription factors. The team proposes an alternative theory: there is one rare stem cell type that is unique in its ability to be reprogrammed into different types of cells.

It is the first time that synaptic density has been measured in living people with autism.

Furthermore, the research team found that the fewer synapses an individual had, the more features of autism they exhibited.

The findings appear in Molecular Psychiatry.

Continue reading “Brain difference tied to autism found in living people for 1st time” »