Lifeboat Foundation

Yesterday Daniel Dennett died. He was 82, about the same age as my father when he died a few years ago.

Rice University researchers have developed a new implantable sensor, spinalNET, capable of recording the electrical activity of spinal neurons in freely moving subjects. This breakthrough could help unlock the complexities of how spinal neurons process sensory and motor functions, potentially leading to better treatments for spinal cord diseases and injuries.

Implantable technologies have significantly improved our ability to study and even modulate the activity of neurons in the brain. However, neurons in the spinal cord are harder to study in action.

“If we understood exactly how neurons in the spinal cord process sensation and control movement, we could develop better treatments for spinal cord disease and injury,” said Yu Wu, a research scientist who is part of a team of Rice University neuroengineers working on a solution to this problem.

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.

Dr Anne Hahn and Associate Professor Steven Zuryn from UQ’s Queensland Brain Institute said the findings could provide a promising therapeutic avenue to stop the onset of heritable and age-related diseases.

“Mitochondrial DNA is essential for cell function,” Dr Hahn said.

Dr. Matt Lyon, MD: “We are not entirely sure what causes these issues with vision, but we suspect it has to do with a shift in cerebrospinal fluid in the optic nerve sheath. On Earth, gravity pushes that fluid down and it drains out, but in space, it floats up and presses against the optic nerve and retina.”

How does spaceflight affect vision loss in astronauts for both the short and long term? This is what a combined effort between the upcoming Polaris Dawn mission and the Medical College of Georgia (MCG) at Augusta University hopes to achieve as the four-person crew will be using a portable ultrasound machine to study changes in vision during spaceflight. This is especially prevalent since the four-person crew will be traveling in an elliptical orbit 870 miles above the Earth’s surface, exposing them to the Van Allen radiation belt, which is a highly radiated region of space between the Earth and the Moon.

For context, the International Space Station orbits approximately 250 miles above the Earth, and this research holds the potential to further explore the effects of space radiation on the human body, and specifically vision loss.

Continue reading “Mitigating Spaceflight Vision Risks: The Role of Portable Ultrasound in Polaris Dawn” »

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Nobel Prize winner Roger Penrose famously believes that the collapse of the wave-function in quantum mechanics causes consciousness. A group of physicists now tries to improve on Penroses idea in a new paper. I have some comments…

Continue reading “Can Quantum Physics Explain Consciousness After All?” »

A new study, funded by the National Institute of Mental Health and the National Institute of Neurological Disorders and Stroke, describes a promising way to carry genetic material into the brain to reach cellular targets.

The city is considering whether to spend federal funds to offer personalized transcranial magnetic stimulation, or PrTMS, to public safety personnel who may feel groggy from poor sleep or want to improve interactions with the public.

Dr. Kevin Murphy explained the drug-free, noninvasive therapy at workshops Monday in Turlock. Therapy performed in a clinic directs magnetic pulses to stimulate electrical activity in neurons in the brain to regulate moods and restore mental well-being. The treatment is tailored for each individual based on an EEG and mapping of brain activity.

Murphy said the benefits for first responders will be fewer injuries and complaints, better sleep and employee satisfaction. The doctor said improved sleep is a common denominator for people who come into the clinic struggling with different issues.

Summary: New research in mice reveals that aging slows the brain’s ability to clear out harmful waste, contributing to neurological disorders like Alzheimer’s and Parkinson’s. Scientists have found that restoring function in the brain’s waste-clearing system, known as the glymphatic system, can reverse these age-related effects.

Using a clinically approved drug, researchers increased the efficiency of waste removal, offering a potential treatment strategy for age-related brain diseases.

A task in which participants learned to perform inference led to the formation of hippocampal representations whose geometric properties reflected the latent structure of the task, indicating that abstract or disentangled neural representations are important for complex cognition.